We measure blood pressure in the clinic and we treat hypertension. And we should. We measure blood pressure in the hospital and we treat hypertension. But Should we?
Modern medical education doesn’t go to the comparative physiology well very often. So when we do, it is always fresh and exciting. Join the Filtrate as we explore the fascinating world of the Gila Monster and Mourning Dove.
Freely Filtered 059: Another dogma shredding trial about diuretics, this time torsemide goes up against king furosemide and its ability to prevent rehospitalization CV events.
Freely Filtered 060: Hydrochlorothiazide has long been said to prevent calcium-based kidney stones and then a well done blinded trial showed, that it’s complicated. Join The Filtrate for a masterclass on this landmark trial.
Freely Filtered 056: MYTEMP is the largest dialysis trial. 15,000 patients, 4.3 million dialysis treatments. We bring in lead PI Amit Garg to help break it down the trial and its implications.
Freely Filtered 054: EMPA-Kidney. EMPA-Kidney is the last of the big three to report their Kidney Endpoints SGLT2i trial (CREDENCE for Cana, DAPA-CKD for Dapa, and now EMPA-Kidney for Empa) and it answers some questions that had previously been unanswered. Join the Filtrate as they tear it apart.
Freely Filtered 051: ADVOR turns the practice of sequential nephron blockade on its head by blocking the proximal tubule before the loop of Henle. Does it work? Join The Filtrate as we dissect the latest diuretic RCT.
Episode 049: SODIUM-HF is the largest and longest RCT done looking at sodium restriction heart failure. The top line results show no effect but the more you look at the study the more problematic it is. The Filtrate take it to task.