Background
Cristina Adriana Popa
Advance-HTN: Return of the systolic order – ...

This week, we will discuss a NEJM trial on uncontrolled hypertension: lorundrostat, an aldosterone synthase inhibitor, aims at the hormonal dark side driving resistance.

Advance-HTN: Return of the systolic order – Lorundrostat’s role in restoring balance
Background
swapnil hiremath
Double Trouble: ddAVP and the Bleeding Biopsy

This week, we will discuss a double header: two single centre ddAVP trials in kidney biopsy from India.

Double Trouble: ddAVP and the Bleeding Biopsy
Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review

Our newsletter just went out and it is a doozy

Did we mention we had a news letter? (please sign up)

If you were on the mailing list, you can see the letter here. The e-mail covers three important pieces of NephJC news

1

Our next TweetChat is next Tuesday at 9 PM. We are looking at the NEJM article about VUR prophylaxis. Interesting paper. Pascal Lane did a wonderful summary of the study.

2

We are changing the way we do video interviews. These will no longer be scheduled events but, instead will get done when we can arrange a time with the most interesting scientists willing to talk to us.

3

We are exploring the possibility of doing a Live NephJC during Kidney Week in Philadelphia. We have a four question Survey Monkey to try to gauge how much interest there is in this idea.

NephJC.com user statistics

I have been a dedicated Mac user since 1991 and the turn around that Apple has pulled off never ceases to amaze me. Look at the OS distribution of readers of NephJC.com. Apple has 59% of visitors between iPhone and MacOSX. Incredible.

But I don't think all of the credit can be given to Stevie J and his merry band of Nexters. Look at the twin debacles of Vista and Win8. Together, those two OS's can't smell the OS share of XP whose latest update was over 6 years ago!

Just got a great e-mail from a lurker

Just after we finished the Mesoamerican Nephropathy twitter chat I received the following e-mail:

What a great comment. We usually measure success by the number of people that engage in the conversation but there is another group of people who listen without talking. Great to hear from one of them to remind us that there are multiple ways to get value from NephJC.

Big props to Nature Reviews Nephrology for opening up their #NephJC article

The editors of Nature Reviews Nephrology were some of NephJC's earliest supporters. One of the ways they supported us was by suggesting an article for discussion. We decided to use that article and they even made that article open access. This is a limited time offer so make sure you run over to their site and download the study. We are so appreciative of all the support the crew at Nature Reviews Nephrology has offered NephJC. Thank-you guys.

We will be discussing this interesting Perspective on Twitter at 9PM Eastern on Tuesday July 8. Use hashtag #NephJC.

Google Hangout in 90 minutes!

NephJC will be doing a live Google Hangout tonight, Tuesday at 9pm EDT. We will have Somjot Brar, the lead author of POSEIDON and Peter McCullough cardiologist and expert on contrast nephropathy joining Joel Topf.

We will try to take questions from people watching, so tweet your questions with the hashtag #NephJC and we will forward them on to our panel of experts.

At the end of the discussion we will announce the next NephJC article.



We have a winner to the coffee challenge!

Last week in the e-mail announcement for the TweetChat we had a trivia contest. We asked what has more sugar, a lightly sweetened cup of coffee or all of the plasma in all of the body of an euglycemic adult?

Almost immediatly we got the following tweet:

Which is correct! Eoin will be enjoying his lightly sweetened coffee from a new NephJC coffee mug just as soon as the boat delivers it across the pond. Congratulations Eoin!

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