Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review
Background
Cristina Adriana Popa
REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨

REGENCY: A B-Cell Super Destroyer in Lupus
Background
Cristina Adriana Popa
Hunting Primary Hyperaldosteronism: are MRAs a ...

This week, we will continue with February’s aldosterone leitmotif: do mineralocorticoid receptor antagonists (MRAs) truly blind the diagnostic in unilateral hypraldosteronism? Is this the article the mythbuster? Draw your own conclusions

Hunting Primary Hyperaldosteronism: are MRAs a blindfold in adrenal vein sampling?

#KidneyWk14 Social Media Awards The #TNOTs

As part of NephJC live we will be awarding social media awards. We will be giving recognition and prizes for:

  • Best use of Twitter during Kidney Week
  • Best Storify on Kidney Week
  • Best Blog post on Kidney Week
  • Best Fresh Face for a person new to the social media scene making an impact at Kidney Week

If the use of social media has not rocketed you up the academic ranks, it is probably because you have no awards to show for it. Come to NephJC Live and get the recognition you deserve! Remember NephJC founders are not eligible for prizes.

The awards for social media will be decided by a blue ribbon panel made up by, our two speakers, Drs. Sawinsky and Wilson; our two founders, Drs. Topf and Swapnil; and Ivan Oransky and Kristina Fiore of MedPage Today.

We need submissions for best use of social media. So tweet links to examples with the hashtag #TNOT (Top nephrologist of twitter).

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Humble beginnings

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I had thought of starting a Nephrology Journal club ever since I wrote about eJC on PBFluids. In fact if you look at my suggestions for how to improve CJASN eJC, you will see the skeleton for the current #NephJC. But ideas are cheap and I never did anything about it.

In the middle of NephMadness last year I received a tweet from from Swapnil suggesting that someone do a Nephrology Twitter Journal Club. I told him it was a great idea but that I had my hands full with NephMadness and that he should write me after the contest ended.

Literally moments after we announced the winner of NephMadness, Swapnil e-mails me about the journal club. I told him to do some research on how twitter journal clubs work and write a post on Medium. I half hoped he would drop the ball and go away but he published it on April 17. A week later we collaborated on a tighter introduction, also published on Medium (we didn't yet have our SquareSpace sight) And five days after that we held our first NephJC.

Last call for #NephJC Live

We are closing registration for NephJC Live this Sunday so register today if you want to be a part of the first NephJC Live event. We have two young investigators who will be sharing their data. We will be awarding the Social Media Awards for the best contributors to the conversation around Kidney Week and we will have lunch!

All the details are available here.

Register before it is too late!

#NephJC goes again tomorrow November 4 with Steigerwalt and @Nephro_Sparks

We have covered a lot of subjects in our first half year but tomorrows study is unique. For the first time NephJC is going to tackle a basic science paper. In order to make this work we are bringing in a couple of ringers.

  • First, we got Dr Susan Steigerwalt, a renowned hypertension specialist who has had a ringside seat for every significant hypertension study of the past two decades. While we were reading about these studies in our pajamas, Dr Steigerwalt was in the trenches calibrating mercury sphygnomamoters. She wrote an in-depth summary of the article that is available at NephJC.com. Don't miss it.
  • The other ringer is Matt Sparks. You may know him from his high profile roles at the Renal Fellow Network, where he played a critical role in saving this institution after the tragic death of Nathan Hellman and or his role as a founder of AJKDblog. But what you probably don't know is that in addition to being a blogger he is a basic science researcher and has sophisticated knowledge about this very paper. We are delighted that he has agreed to step up to the table to spin those wheels of steel and host the @NephJC twitter account tomorrow as we do a deep dive on Harrison's land mark article on T cells and the genesis of hypertension.

The article is a doozy, so make sure you do your homework. Help us make this very special basic-science episode of NephJC a success.

Swapnil hits the mainstream media!

Swapnil Hiremath, is the co-founder of NephJC and his research was recently highlighted in Time Magazine, as in Time Man of the Year, Time Magazine. Awesome work, I can't wait to see his data at ASN Kidney Week. Way to go Swapnil!

If you are interested in the issue that Swapnil investigated, this article may provide some additional useful data.

UPDATE: Swapnil also made the ASN In the Loop e-mail blast on October 30. Wow.

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NephJC.com: how people get here

Last week I tweeted:

I received varied response, Pascale Lane and Michael Katz agreed, while Dr. Canapari disagreed:

And Matt Sparks called me directly to tell me that I was crazy; the analytics he has access to show search by a mile.

Here is the data for the last month at NephJC, Direct links (bookmarks, e-mail links, hand typed URLs, others?, etc) and Twitter (t.co) represent 75% of traffic with Google mopping up a distant third.

How to embed a Storify into a blog post

Some very clever people have asked me how to embed a Storify into a blog post. Here are some step by step instructions.

  1. go to the Storify page with the content you want to embed
  2. Click on </> Embed (upper right corner)
  3. Click on show templates
  4. NephJC tries to always use the slide show format
  5. We also use full header and a border
  6. Elect and copy the embed code HTML in the box
  7. In the SquareSpace blog post add a code block </>
  8. Paste the embed HTML over <p>Hello, World!</p>
  9. Save

New to Twitter? Wondering who to follow?

Twitter is a strange a service, because if you don't follow anyone it is about as useful as the first telephone. Value only emerges as your follow list evolves. One of the missions of NephJC is to bring nephrologists together for twitter events so people can find other interesting people develop there own network. If you don't pick up 1 or 2 new people to follow at every #NephJC discussion either we are doing a bad job or you're doing it wrong.

The value of Twitter is related directly to the quality of the people you follow. In the  spirit of helping people get started on Twitter we are going to recommend accounts to follow on Twitter. This first edition is about official accounts.

CRIC: Chrinic Renal Insufficiency Cohort. The most important observational study in CKD ever conducted.

KDIGO: Global nephrology clinical practice guidelines

ERA-EDTA: European nephrology professional association

ASNKidney: The big kahuna.

RenalMed: Free online nephrology resources

NatureRevNephrology: Editors of Nature Reviews Nephrology

Andrew Narva: Director of of the NKDEP using twitter to fight the good fight

Richard Lehman: Simply the best commentator on internal medicine research in the world.

Kidney News: News magazine for the ASN

NEJM: The Journal of Record

JAMA: Wants to be The Journal of Record

CJASN: New to the show, show them some follow love. Only 22 followers. Really?

eAJKD: the blog of the AJKD with 1200 followers. Hey, CJASN, this is how it's done!

The International Society of Nephrology. ASN but for the world.

Canadian Society of Nephrology. ASN but for the Great White North