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NephJC

Queue
Flozinator
Blog
PodCast
More
Club de Articulos
Code of Conduct
The Why, When and How
The NephJC Organization
Twitter Journal Club Primer
Who are we
Masthead
COVID19
Seminars in Nephrology
Regarding Twitter...
Newsletter
May 26, 2025
Background
Cristina Adriana Popa
Advance-HTN: Return of the systolic order – ...

This week, we will discuss a NEJM trial on uncontrolled hypertension: lorundrostat, an aldosterone synthase inhibitor, aims at the hormonal dark side driving resistance.

Advance-HTN: Return of the systolic order – Lorundrostat’s role in restoring balance
May 12, 2025
Background
swapnil hiremath
Double Trouble: ddAVP and the Bleeding Biopsy

This week, we will discuss a double header: two single centre ddAVP trials in kidney biopsy from India.

Double Trouble: ddAVP and the Bleeding Biopsy
April 28, 2025
Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
April 14, 2025
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
March 23, 2025
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review
joel topf
August 3, 2016
Background

NINJA: A systematic approach to reduce exposure to nephrotoxins

joel topf
August 3, 2016
Background
NINJA: A systematic approach to reduce exposure to nephrotoxins

#NephJC will be looking at the NINJA trial which implemented a automated mechanism to alert doctors of nephrotoxic medications. Initiating this system correlated with a dramatic and persistent drop in acute kidney injury.

Tagged: Rheault, NINJA

joel topf
August 1, 2016
storify, Background

#NephJC Book Club: the wrap up #PWSYN

joel topf
August 1, 2016
storify, Background
#NephJC Book Club: the wrap up #PWSYN

Despite the summer and vacations, we had two very successful chats. This post has links to the full archive of the discussion as well as two curated Storifys.

Tagged: Topol, PWSYN, storify, Book Club

joel topf
July 26, 2016
Commentary

Chapter Fifteen: The Emancipated Consumer

joel topf
July 26, 2016
Commentary
Chapter Fifteen: The Emancipated Consumer

In the final chapter Topol discusses what needs to happen in order to get from where we are now to a truly emancipated patient. It is a tall order. Dr. Sparks dissects the chapter.

Tagged: Sparks, Topol

joel topf
July 23, 2016
Commentary

Chapter Fourteen: Flattening The Earth

joel topf
July 23, 2016
Commentary
Chapter Fourteen: Flattening The Earth

In the penultimate chapter, Topol turns to the developing world and how digital technologiee have the potential to improve health for the poorest humans.

Tagged: Oates, Topol

joel topf
July 23, 2016
Commentary

Chapter Thirteen: Predicting and Preempting Disease

joel topf
July 23, 2016
Commentary
Chapter Thirteen: Predicting and Preempting Disease

Special guest Scott Brimble reviews the thirteenth chapter on predicting and preempting disease. Scott adapts the lessons of David Sackett and has a skeptical angle on the chapter.

Tagged: Brimble, Topol

joel topf
July 23, 2016
Commentary

Chapter Twelve: Secure vs. Cure

joel topf
July 23, 2016
Commentary
Chapter Twelve: Secure vs. Cure

Topol takes on privacy and security in our digital world. This is the darkest chapter of the book. It is filled with problems and the answers he poses seem thin and inadequate.

Tagged: Topf, Topol

joel topf
July 23, 2016
Commentary

Chapter Eleven: Open Sesame

joel topf
July 23, 2016
Commentary
Chapter Eleven: Open Sesame

Intelligent analysis of all the big data we are on the verge of creating in medicine will be the engine that drives future innovation. In cahpter 11, Dr. Topol outlines how open source organization will allow us to harness the potential of this data.

Tagged: Goldman, Topol

joel topf
July 22, 2016
Commentary

Chapter Ten: The Edifice Complex

joel topf
July 22, 2016
Commentary
Chapter Ten: The Edifice Complex

In chapter ten, Dr. Topol describes the hospital of the future which will be very different than today's hospital. Dr. Daniel Coyne is not convinced.

Tagged: Coyne, Topol

joel topf
July 21, 2016
Commentary

Chapter Nine: My (Smartphone) Doctor

joel topf
July 21, 2016
Commentary
Chapter Nine: My (Smartphone) Doctor

Eric explores how digital tools will allow virtualization of the entire medical encounter. Hello Tricorder.

Tagged: Topol, Madariaga

joel topf
July 21, 2016
Commentary

Chapter Eight: My Costs

joel topf
July 21, 2016
Commentary
Chapter Eight: My Costs

In chapter 8 Topol looks at the absurd costs of medical care. He also shines a light on possible solutions. Dr. Burgner takes us through it.

Tagged: Burgner, Topol

joel topf
July 21, 2016
Commentary

Chapter Seven: My Records and Meds

joel topf
July 21, 2016
Commentary
Chapter Seven: My Records and Meds

Tool looks at electronic medical records and how they can be the bridge to better care. He discusses the potential for EMRs to allow patients to have real access to their medical information. Also pills with electronic trackers.

Tagged: Topol, Iannuzzella

joel topf
July 21, 2016
Commentary

Chapter Six: My Lab Tests and Scans

joel topf
July 21, 2016
Commentary
Chapter Six: My Lab Tests and Scans

In this chapter Topol discusses the future of lab tests. It is a bit dated as he lauds Theranos prior to their implosion, so it is a kind of trip down memory lane.

Tagged: Topol, Byrd

joel topf
July 21, 2016
Commentary

Capter Five: My GIS

joel topf
July 21, 2016
Commentary
Capter Five: My GIS

GPS is so successful at concurring location that getting lost is outdated. Eric discusses The personal GIS, or geographic information system that integrates all the 'omics of a single individual and which could make medicine outdated.

Tagged: Topol, Hiremath

joel topf
July 19, 2016
Commentary

Chapter Four Angelina Jolie: My Choice

joel topf
July 19, 2016
Commentary
Chapter Four Angelina Jolie: My Choice

Chapter Four. The intersection of genes, breasts and the power of celebrity. The story of Angelina Jolie's choice and how it changed the conversation on patient empowerment.

Tagged: Rheault, Topol

swapnil hiremath
July 18, 2016
Commentary

Chapter Three: A Precedent for Momentous Change

swapnil hiremath
July 18, 2016
Commentary
Chapter Three: A Precedent for Momentous Change

Topol goes deep into the revolution that was the printing press and how similar it looks to the current smartphone revolution.

Tagged: Topol, Hiremath

joel topf
July 18, 2016
Commentary

Chapter Two: Eminence-Based Medicine

joel topf
July 18, 2016
Commentary
Chapter Two: Eminence-Based Medicine

Paternalism has defined the doctor-patient relationship for millennia. However this aspect of medical cultureis collapsing. Dr. Lerma dissects chapter 2, a deep dive into medical paternalism.

Tagged: Topol, Lerma

joel topf
July 16, 2016
Commentary

Chapter One: Medicine turned Upside Down.

joel topf
July 16, 2016
Commentary
Chapter One: Medicine turned Upside Down.

Eric Topol begins this book by setting the stage of why patients will become more empowered. Topol argues that patients are not going to settle for the amount of power physicians are comfortable yielding, but rather that forces larger than medicine will fundamentally alter the traditional patient-doctor relationship.

Tagged: Topol

joel topf
July 15, 2016
Meta

The NephJC Summer Book Club is coming

joel topf
July 15, 2016
Meta
The NephJC Summer Book Club is coming

You still have time to buy Eric Topol's The Patient Will See You Now in time to be ready for #NephJC's summer book club. We will be discussing this on July 26 and 27 at the usual @NephJC times.

Tagged: Topol

swapnil hiremath
July 15, 2016
storify

The #NephJC Pip/Taz + Vancomycin chat wrap up

swapnil hiremath
July 15, 2016
storify

Storify for both chats

Transcripts

American Chat Transcript
EU chat Transcript

Tagged: AKI, drug, storify, transcript, Hiremath, PipTazo

joel topf
July 10, 2016
Commentary

Required reading for This Week's Chat

joel topf
July 10, 2016
Commentary

The introduction by Matt Graham-Brown is excellent but I think the post by Josh Farkas will be a major influence on the discussion. Don't miss it.

Tagged: PipTazo

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