Is Apolipoprotein E a new biomarker for DDD and C3GN?
NSMC Intern Dr Jasmine Sethi decodes the recent study visually
This week, we will discuss the use of creating chimeras to induce immune tolerance and its potential to decrease or eliminate the need for immunosuppression in kidney transplant recipients.
This week, we will discuss the AHA/ACC 2025 hypertension guideline update. Wow, have eight years flown by?
This week, we will discuss the ACHIEVE trial. Will spironolactone achieve CV benefits in ESRD?
The summer book club started in 2015, with one of the best books we have done in book club, Atul Gawande's Being Mortal. I think it should be required reading for all physicians. So now, in 2025, it is the NephJC Summer Book’s tenth anniversary (which represents our eleventh book). The history has been rich:
Does targeted-release formulation of Budesonide improve kidney function in primary IgA Nephropathy? Check out the VA by NSMC Intern Anant Pilawan on NefIgArd part B trial
NSMC Intern Elba Medina creates a crisp VA for the PRAECIS trial.
Also, we have some bonus VAs this time created for NephMadness by our VA editor Divya Bajpai!
Check out the dreamy Visual Abstract by Cristina Popa
Any sleep potion for insomnia in patients on hemodialysis?
Trainee Love and Breakup Letters to NephSIM: A Free, Mobile-Optimized, Nephrology Teaching Tool (Fattah, CJASN 2023)
Intensive BP Control in Patients with CKD and Risk for Adverse Outcomes (Ku, JASN 2023)
Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries (Marcum, JAMA Open Network 2022)
Angiotensin receptor blockers for the treatment of covid-19: pragmatic, adaptive, multicentre, phase 3, randomised controlled trial (Jardine, The BMJ 2022)
The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial (Voors, Nature Medicine 2023)
Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial (Mackenzie, The Lancet 2023)
Tissue sodium excess is not hypertonic and reflects extracellular volume expansion (Rossitto, Nature Communications 2020)
CYP1A2 Genetic Variation, Coffee Intake, and Kidney Dysfunction (Mahdavi, JAMA Network Open 2023)
Effectiveness of an Intervention to Improve Decision Making for Older Patients With Advanced Chronic Kidney Disease (Ladin, Annals Int Med 2023)