Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review
Background
Cristina Adriana Popa
REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨

REGENCY: A B-Cell Super Destroyer in Lupus
Background
Cristina Adriana Popa
Hunting Primary Hyperaldosteronism: are MRAs a ...

This week, we will continue with February’s aldosterone leitmotif: do mineralocorticoid receptor antagonists (MRAs) truly blind the diagnostic in unilateral hypraldosteronism? Is this the article the mythbuster? Draw your own conclusions

Hunting Primary Hyperaldosteronism: are MRAs a blindfold in adrenal vein sampling?

Does Contrast cause acute Kidney Injury?

Does Contrast cause acute Kidney Injury?

Iodinated contrast is well known to cause acute kidney injury (AKI), mainly from its physico-chemical properties, and is the commonly cited as being the third most common cause of AKI in hospitalized patients. But is this really true? Even the term contrast-induced AKI (CI-AKI) is now being increasingly replaced by contrast-associated AKI (CA-AKI), and could contrast be an 'innocent bystander'?

#NephJC on the facebook app: wrap up

We had a few hiccups for this chat: the authors, Komal Kumar, Betsy King did join us for the first chat - and so did some other staff from Hopkins ERGOT workgroup, but twitter gave a lot of troubles the next day. Tweets were not showing up - so we called it a day, and rescheduled the chat to Sep 28. Things did work out this time!

Does Regional Anesthesia Improve Fistula failure rates? The #NephJC wrapup

Fistula Failure: Can Anesthesia Solve our Vexing Vascular Access Problems?

Fistula Failure: Can Anesthesia Solve our Vexing Vascular Access Problems?

Historically nephrology is a specialty that has been criticized for it’s inability to produce high quality randomized controlled clinical trials designed to answer a specific question. So, when the Lancet publishes the results of a clinical trial in the field it is worth taking note.