Which were the Top Nephrology Stories of 2024?

In 2010 Matt Sparks started the longest tradition in Nephrology Social Media, The Top Nephrology Stories of the Year. In 2017, this project moved from the Renal Fellow Network to NephJC, where it has been hosted ever since. Here are all 8 of the NephJC Top Stories.

So which stories should be the top stories of 2025? Here are the nominees, listed below.

Only current NephJC newsletter subscribers can vote. At the bottom of this post, down below, you can see a button to subscribe - do it before we send out the survey if you want to have your say on the top stories of 2025!

1. ACHIEVE: spironolactone versus placebo in patients undergoing maintenance dialysis (Link | NephJC summary)

2. PISCES: Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis (Link | Kidney Week Day 2| NephJC summary)

3. All IgA trials: VISIONARY (Link | Kidney Week Day 3), ORIGIN-3 (Link | NephJC summary), APPLAUSE-IgAN (Link)

4. REGENCY trial (Link | NephJC summary)

5. Hypertension AHA/ACC guidelines (Link| NephJC summary)

6. POTCAST: increasing K levels in patients with high risk of ventricular arrhythmia (Link)

7. The (ongoing?) dawn of aldosterone synthase inhibitors (Link | NephJC Shorts)

8. BedMed- recapping the chronotherapy story (Link | NephJC Shorts)

9. Iptacopan in C3 glomerulonephritis (Link)

10. Nobel winner peripheral immune tolerance: kidney transplant application (NephJC commentary) and CAR-Ts in nephrology (CAR-Ts NephMadness)

11. Paradigm shift: aiming for CKD remission, not just slowing it (Link)

12. Guideline-directed medical therapy- closer to implementation: CONFIDENCE (Link | NephJC summary), MIRO-CKD (Link | Kidney Week Day 3)

13. Safety of Kidney Transplantation from Donors with HIV (Link)

14. Dialysis decline in the US (Link)

15. Flozins metas: all across subgroups
    SMART-C group: Kidney Week Day 2 coverage: Neuen B, et al; Staplin N et al
    Empagliflozin individual-level meta-analysis (Link | NephJC shorts)

16. Global burden disease of CKD (1990-2023) (Link | Kidney Week Day 2)

17. SuPAR causes renal vasoconstriction and may cause AKI? (Link)

18. Xenotransplantation progress (Link), and the FDA allows clinical trials (Link)

19. Navigate-Kidney: social workers against interdialytic weight gain (Link | Kidney Week Day 2)

20. GLP1-RA: 2025 progress: REMODEL trial (Link), SURPASS-CVOT trial (Link)

21. Proteinuria (beyond nephrology)= indicator of renal and cardiovascular risk (Link)

22. A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2) (Link)

23. NIDDK 75th Anniversary- couldn’t enjoy a proper celebration because of the lack of gov funds (Link)
    

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