In 2010 Matt Sparks started the longest tradition in Nephrology Social Media, The Top Nephrology Stories of the Year. In 2017 this project moved from Renal Fellow Network to NephJC, where it has been hosted ever since. Here are all 6 of the NephJC Top Stories (The 2017 post has links to the 7 prior editions on the Renal Fellow Network for you nostalgic types).
So which stories should be the top stories of 2023? Here are the nominees, with a link to vote at the bottom.
Endothelin antagonists advance (PROTECT link and link | NephJC Summary; DUPLEX link | NephJC summary; ZENITH link | NephJC Summary)
Inaxaplin phase 1 trial in APOL1 (NEJM link | NephJC summary | Freely Filtered podcast)
ENAKT-LD at Kidney Week, simulcast freely filtered podcast release (JAMA IM link | NephJC Summary | Freely Filtered podcast)
The Kidney Precision Medicine Project (Nature link | NephJC Summary)
Urine CXCL-9 in AIN (JCI link | NephJC Summary)
Hemodiafiltration better than hemodialysis, finally CONVINCEd? (NEJM link | NephJC summary)
Balanced Fluids best Saline in Transplant (BEST Fluids, Lancet link | NephJC Summary)
HCTZ doesn’t prevent stones (NEJM link | NephJC summary | Freely Filtered Podcast)
Diuretics: just a class effect after all (DCP NEJM link | Transform HF JAMA link | NephJC summary DCP and Transform HF | Freely Filtered podcast DCP and TRANSFORM HF)
Falling dialysis numbers (USRDS ADR)
The rise of Aldosterone synthase inhibitors (Baxdrostat, NEJM link | Lorundrostat JAMA link | BI690517 Lancet link)
Hyponatremia correction: Speeding doesn’t Kill? (NEJM Evidence link | NephJC Summary)
Preclampsia diagnostic test ( NEJM Evidence link | Thermo Fisher link)
Polygenic risk alters Monogenic risk penetrance? (Khan et al, Nature Comm link)
Demand for Nephrology Fellowships remains soft (ASN Data Analytics link | PB Fluids blog)
The ERA gets a woman president, Roser Torra!
IgA Nephropathy: The commonest GN gets a few drugs with evidence and approval! (Sparsentan approval | Budesonide NephJC summary Lancet link )
Anticoagulating Atrial Fibrillation: 3 trials, but no surety yet (RENAL AF Circulation link | AXADIA Circulation link | NephJC summary | SAFE-D at KidneyWk)
Renal denervation finally approved in the US by the FDA (ReCor/Otsuka | Medtronic | RADIANCE final results | SPYRAL final results | NephJC summary from 2018)