Does Torsemide lower all cause mortality compared to furosemide for heart failure patients post-hospitalization? Cristina Popa elaborates, visually!
The Diuretic Comparison Project Visual Abstract
Is Chlorthalidone superior to Hydrochlorothiazide in preventing major adverse cardiovascular events? Here is the VA from Mike Turk
The good news is there was a huge trial in Alport syndrome published
The bad news is it was on bardoxolone. Tweetorial catch-up here.
Freely Filtered does STOP ACE
Episode 055: The Filtrate try to figure out STOP ACE with the assistance of Laurie Tomlinson.
The CARDINAL Visual Abstract
Does Bardoxolone help patients with Alport’s Syndrome? Dr M Abdul Qader explains graphically.
CARDINAL Sin: Bardoxolone and Alport Syndrome
IgA and steroids: the saga continues
Drug reps pitching you Nefecon? Catch-up with the RCT in our #TenTweetNephJC tweetorial
NefIgArdians of The Glomerular Galaxy
NefIgArd trial : Visual Abstract
Check out the Delightful Visual Abstract for the NefIgArd trial by Priti Meena
The Top Nephrology Stories of 2022
Introducing "NephJC Collections"
Checking in on MyTEMP - #TenTweetNephJC
The last NephJC of the year brought us a cool discussion on if cooling dialysate could help mitigate the effects of intradialytic hypotension. Get caught up with the chat in the latest edition of #TenTweetNephJC.
Freely Filtered does minimal change disease and anti-nephrin antibodies
Episode 042: Minimal change disease has classically been described as having negative immunofluorescence and to not be antibody mediated. But here comes Dr Weans with a fresh study smashing this orthodoxy. She proposes anti-nephrin antibodies as the etiologic agent driving minimal change disease.
Freely Filtered does Xenotransplantation
Episode 044: The University of Alabama with Revicor have made a better pig. Better for transplanting. And they transplanted a pair of these into a brain dead patient. The filtrate discuss the case report with transplant surgeon, Josh Mezrich.
Freely Filtered does SSaSS
Episode 045: Switching table salt to a blend of sodium and potassium chloride reduces stroke and improves total mortality. What’s not to like?
Freely Filtered does ISPD Peritonitis Guidelines
Episode 046: The Guideline Draft is back! This time the 2022 ISPD Peritonitis Guidelines are on the clock! The Filtrate are joined by PD junky Jade Teakell and guideline author, Jeff Perl.
Freely Filtered does CHAP
Episode 047: This is a guideline shredding study. This landmark study of blood pressure in pregnancy is going to change how we approach hypertension in pregnancy.
Freely Filtered does TESTING-2
Episode 048: TESTING is the latest IgA nephropathy trial and it is the comeback kid of nephrology trials. From a trial that was halted because of excess adverse events to a safe and effective therapy with just a few tweeks. Amazing turn around. Join the Filtrate as we put TESTING to the test with study author Sean Barbour.
Freely Filtered does SODIUM-HF
Episode 049: SODIUM-HF is the largest and longest RCT done looking at sodium restriction heart failure. The top line results show no effect but the more you look at the study the more problematic it is. The Filtrate take it to task.
Freely Filtered does The Classic Trial
Freely Filtered 050: CLASSIC Trial. The Filtrate look at the latest contribution to Fluid Wars, this one looking at late resuscitation.