Freely Filtered 045: Salt Substitution and Stroke Study (SSaSS)

The SSaSS study is a landmark study in the study of sodium and its effect on blood pressure and mortality. Join the Filtrate as they do a deep dive.

The Filtrate:

Joel Topf

Joshua Waitzman

Nayan Arora

Jennie Lin

Sophia Ambruso

Special Guest:

Paul A Welling

Editor:

Sophia Ambruso

Show Notes:

NephJC Summary on SSaSS

Paul Welling’s tweetorial on the potassium switch

The 2016 Canadian Hypertension guidelines were the first to suggest adding potassium: Hypertension Canada's 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension

Swapnil’s Potassium Trial: Diet or additional supplement to increase potassium intake: protocol for an adaptive clinical trial

When Food Firms Cut The Salt, What Do They Put In Instead? From NPR.

Effect of increased potassium 🍌 intake on cardiovascular risk factors and disease: systematic review and meta-analyses

Effect of lower sodium🧂 intake on health: systematic review and meta-analyses

Estimated population wide benefits and risks in China of lowering sodium through potassium enriched salt substitution: modelling study

FDA Issues Final Guidance Regarding Use of an Alternate Name for Potassium Chloride in Food Labeling

David Ellison and Paul Welling’s reviewing the NEJM: Insights into Salt Handling and Blood Pressure

NephTrials on Cluster Randomized Trials: http://www.nephjc.com/news/clusterct

Nu-Salt (KCl) 3 oz for $4.97 at Amazon (no afiliate link because we don’t have our act together)

Salt for Life looks like it is 75% KCl 25% NaCl and it is 11.99 for 10.5 oz at Amazon (see above disclaimer)

Bridgerton, only 8 episodes for Season 2

Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1: The Paper | The Tweet

Kansas wins March Madness

Work in Josh’s lab. Get in touch: jswaitzm@bidmc.harvard.edu

Open Educational Resources (OER)

NKF Spring Clinical Meeting 2022

Little Podocye