swapnil hiremath

May 28, 2019

Background

Risk Stratifying A Heterogeneous Entity: IgA Nephropathy

swapnil hiremath

May 28, 2019

Background

Risk Stratifying A Heterogeneous Entity: IgA Nephropathy

This week, we will discuss a risk score which helps to prognosticate the most common glomerular disease. Not only is IgA most common - it is quite heterogeneous, which makes the problem of who should get treated quite difficult.

joel topf

May 10, 2019

Background

Fixing Hypernatremia: Acting Fast or Acting Slow?

joel topf

May 10, 2019

Background

Fixing Hypernatremia: Acting Fast or Acting Slow?

They always said not to correct hypernatremia faster than 0.5 mmol/L/hour but what do they know and who are they anyways? New data questions this ancient dogma.

swapnil hiremath

April 22, 2019

Background

The SGLT2i Crescendo with CREDENCE

swapnil hiremath

April 22, 2019

Background

This week, we will discuss the CREDENCE trial, simply the most important nephrology trial in a generation.

swapnil hiremath

April 8, 2019

Background

How can we ASCEND from the depths of depression?

swapnil hiremath

April 8, 2019

Background

How can we ASCEND from the depths of depression?

This week we look at the treatment of depression in hemodialysis patients. It is cognitive behavorial therapy versus sertraline.

swapnil hiremath

March 19, 2019

Background

Newsflash: Numerous NSAIDs are Nephrotoxic

swapnil hiremath

March 19, 2019

Background

Newsflash: Numerous NSAIDs are Nephrotoxic

Its March. Which means it is NephMadness.

In conjunction with NephMadness - Pain Region discussion, we discuss a recent JAMA Network Open study, reporting higher kidney risk in young men taking NSAIDs.

swapnil hiremath

February 24, 2019

Background

The ESA Empire Explodes

swapnil hiremath

February 24, 2019

Background

Can PIVOTAL pivot us to pump more iron? It is indeed a pivot from the lazy, halycon days of the ESA era, now to the evil ESA empire crumbling under the strong iron attack. Join us to discuss!

swapnil hiremath

February 12, 2019

Background

The fault lies in our genes?

swapnil hiremath

February 12, 2019

Background

The fault, is not in our stars, or in our environment, but sometimes in ourselves. Nature, not just nurture, is more important than we knew. Join us, as we try to undertand the implications of this new research suggesting how many CKD cases have genetic underpinnings.

joel topf

January 28, 2019

Background

Nephrology Research. Are we improving?

joel topf

January 28, 2019

Background

We complain about the quality of kidney research but is there any meat there? Join us this week as we look at Chatzimanouil’s recent examination of the nephrology literature.

joel topf

January 14, 2019

Background

Vitamin D in Dialysis is a Dud

joel topf

January 14, 2019

Background

First chat of 2019 - showcasing again the honest brokers of nephrology trials with another negative trial. Also note we will be having a NephJC Asia chat starting this week!

joel topf

December 11, 2018

Background

Single-cell RNA sequencing in the spotlight

joel topf

December 11, 2018

Background

Single-cell RNA sequencing in the spotlight

This week, we go back to basic science with Jennie Lin leading us through two important papers on single cell RNA sequencing.

joel topf

December 2, 2018

Background

Lanreotide rubs the ADPKD lamp but there's no Genie

joel topf

December 2, 2018

Background

Lanreotide rubs the ADPKD lamp but there's no Genie

This week, we will discuss the use of lanreotide - a somoatostatin analogue, for the treatment of autosomal dominant polycystic kidney disease. An RCT, published in JAMA.

joel topf

November 26, 2018

Background

Sirolimus as a Savior for Skin Cancer?

joel topf

November 26, 2018

Background

Join us to discuss this extension of the TUMORAPA trial - in a joint session with the #DermJC. Should kidney transplant recipients with squamous cell cancer be switched to sirolimus?

swapnil hiremath

November 11, 2018

Background

There's just been AKI. So what do we do with the ACEi/ARB?

swapnil hiremath

November 11, 2018

Background

There's just been AKI. So what do we do with the ACEi/ARB?

There is AKI. You are ready to discharge the patient. Should you restart their ACEI/ARB? Or they were never on an ACEI/ARB - but surely with a history of heart failure, they should be on one? How do you decide? Join us to discuss some exciting new data

swapnil hiremath

October 30, 2018

Background

There’s Acid? Give Alkali! Does that really help?

swapnil hiremath

October 30, 2018

Background

There’s Acid? Give Alkali! Does that really help?

This week we discuss the BICAR-ICU trial from France. In patients who are critically ill with metabolic acidosis, does giving bicarb help improve survival? More importantly, does it help with kidney outcomes? Join us to discuss

joel topf

October 11, 2018

Background

Proposition 8

joel topf

October 11, 2018

Background

Proposition 8 is on the ballot. It pits the labor unions against the dialysis corporations. Simple right? Wrong. Check out the details and join us Oct 16.

swapnil hiremath

October 4, 2018

Background

The Structure behind the Function: Unravelling PKD by CryoEM

swapnil hiremath

October 4, 2018

Background

The Structure behind the Function: Unravelling PKD by CryoEM

This week, we discuss some amazing advances made in our understanding of the PKD protein - using a technology called CryoEM. Check out the video explainer and summary.

swapnil hiremath

September 21, 2018

Background

MesoAmerican Nephropathy: More Light on the Heat Hypothesis?

swapnil hiremath

September 21, 2018

Background

MesoAmerican Nephropathy: More Light on the Heat Hypothesis?

Join us as we discuss this study which meticulously collected data from Nicaragua to shed more light on the potential mechanism of mesoamerican nephropathy

swapnil hiremath

August 31, 2018

Background

Antibiotics are bad, the Stone Edition

swapnil hiremath

August 31, 2018

Background

September 4 and 5 we discuss kidney stones and antibiotics. How are the two related, you say? Join us. Find out more!

joel topf

August 18, 2018

Background

Atrial Fibrillation, Anticoagulation and Dialysis: Do We Finally Have A Better Option?

joel topf

August 18, 2018

Background

Atrial Fibrillation, Anticoagulation and Dialysis: Do We Finally Have A Better Option?

Retrospective analysis of apixaban vs warfarin for atrial fibrillation in dialysis patients.

joel topf

August 2, 2018

Background

#NephJCBookClub next Tuesday and Wednesday

joel topf

August 2, 2018

Background

#NephJCBookClub next Tuesday and Wednesday

The fourth annual NephJC Summer Book Club is here and we are reading and discussing, Siddhartha Mukherjee's The Laws of Medicine, Field Notes from an Uncertain Science.