Freely Filtered 004 Hypernatremia

The Filtrate (minus Swapnil) gather to talk about the treatment of hypernatremia.

Show Notes:

Joel Topf

Jennie Lin

Matt Sparks

Samira Farouk


The strange story of Jennifer Strange.

Water Poker

 Nintendo Game Consoles

2019 Narins winner, Mitchel Rosner on MDMA induced hyponatremia

And Rosner again on exercise induced hyponatremia.

The Arieff article on the dangers of severe hyponatremia: Hyponatremia, Convulsions, Respiratory Arrest, and Permanent Brain Damage after Elective Surgery in Healthy Women

The Richard Sterns article on the dangers of rapid correction of hyponatremia: Osmotic Demyelination Syndrome Following Correction of Hyponatremia

The editorial by the man himself, Robert Narins: Therapy of Hyponatremia

The infant study showing seizures associated with rapid correction of hypernatremia.

Follow up study with oral rehydration.

The Linder study of adults admitted to the ICU

French study on patients presenting to the ER with hypernatremia.

Study on US veterans showing poorer outcomes with slow correction of hypernatremia.

Cerebral edema during the treatment of DKA.

The MIMIC 3 Database. MIMIC is an openly available dataset developed by the MIT Lab for Computational Physiology, comprising deidentified health data associated with ~40,000 critical care patients. It includes demographics, vital signs, laboratory tests, medications, and more.

Chalrson Comorbidity Index

The paper: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.

JCI article on organic brain osmnoles in response to hypernatremia

John Booth on the value of MIMIC 3

Sri Lekha on checking labs in hypernatremia

Steve Coca on chunky water administration

Steve Coca musing the Cersei’s sodium level

Steve Coca swearing in High Valarlian:

Steve Coca proving the non-existence of hypernatremia therapy being associated with brain damage through the inability of trial lawyers to find and sue doctors for this issue:

The original paper on the Kardashian Index

Kardashian Index Calculator

Facebook CEO Mark Zuckerberg says the ‘future is private’

Khenar Jhaveri et al on ‘WhatsApp’ening in nephrology training

Mike Morrison’s video on how to rebuild the scientific poster

Mike’s Twitter: with lot’s of examples of his design in the wild.

Make your own QR code:


Ten Worst Drugs for your Kidney:

Drugs that can falsely elevate your creatinine levels:

Dr Orrange, not wishing to engage on Twitter in a meaningful way: