NephJC is a nephrology journal club that uses Twitter to discuss the research, guidelines, and editorials that drive nephrology.
NephJC needs your help. Time to open your wallet and help keep the lights on at NephJC HQ. Also score some pretty fly NephJC fleece, hats and tote bags. (Yeah, we know that there has never been a “fly” tote bag. Work with us.
The NephJC Kidneys return for the fourth year. Time for #NephTwitter to nominate their favs.
Upcoming Twitter chats:
All scheduled chats are tentative. We may change the schedule depending on the whims of the NephJC work group
September 24, 25 #NephJC A clinically applicable approach to continuous prediction of future acute kidney injury
October 8, 9 #AskASN: Renal Educator’s Community
November 19 #AskASN with Michael Allon, editor of Kidney360
December 17 #AskASN with the newly installed president of ASN, Anupam Agarwal
Twice a month, the filtrate (Jenie Lin, Joel Topf, Samira Farouk, Matt Sparks, and Swapnil Hiremath) sit down and recap the latest NephJC discussion. We go as deep as it takes. Give it a listen.
The NephJC Twitter Journal Club Primer
The NephJC work group has produced a primer to document some of our thoughts on the practices on running a Twitter Journal Club. We think it is quite good. Take a look.
In the last year, NephJC has injected some statistical muscle into its editorial team (thank you Perry Wilson and Laurie Tomlinson). Then Manasi Bapat volunteered to create some cogent explainers for the various techniques that are routinely described in the methods section most of us skip over as we rush to the results. Here are the recent posts...
How do you understand the inverted world of non-inferiority? Manasi Bapat breaks it down for us here
She’s back: A stats explainer of statistical modelling, goodness of fit and the Bayes information criterion from Manasi Bapat.
When a study is negative the work is not done. Time to separate a negative trial from an underpowered one. Learn how to think about this with Manasi Bapat.
Propensity scores…what’s up with that?
Multiple testing and the Bonferroni - NSMC intern and NephJC stats explainer Manasi Bapat breaks it down for you in this post.
Manasi deconstructs pragmatic trials for us. How are they different compared to efficacy & explanatory trials?
Manasi Bapat takes you behind the scenes to explain the need for doing sensitivity analyses
We begin a series of occasional commentary on the methods underlying the research being discussed. This edition: the 2 x 2 factorial designs.
The visual abstract for SONAR
The IgA Nephropathy risk score visual abstract
The NephJC Book Club
Every summer we blog our way through a book of medical interest and have a Twitter-based book club discussion.
Some cases of ADTKD are due to mutations of the MUC-1 gene, one mutation is a frame shift mutation that results in a premature stop codon. which results in accumulation of the abnormally short, and toxic protein MUC-1 fs . The researchers found a small protein, BRD4780, that reroute MUC-1fs to lysosomes, preventing proteinopathy and possibly altering the natural history of the disease.
The winners of the third annual NephJC Kidneys
Thanks for voting. On Oct 26th at the #KidneyWk Beach Party we announced the winners in all 5 categories.
Rookie of the Year: Mohamed Elrggal
Most Engaged Scientist: Marvin Gonzalez
Study of the Year: A Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops
Most Valuable Player: Maryam Khosravi
Nathan Hellman Social Media Project of the Year: The GlomCon Interactive Fellows’ Curriculum
See some great pictures from the event here.