Iptacopan decreases proteinuria, now we get the 24-month eGFR data in patients with IgA Nephropathy.
SODa-BIC on Instagram
SODa-BIC on Instagram
A more visual summary of the trial and relevant context (just 6 images to look at!). Infographics by Daniel Ramirez and Urvashi Khan
FIND-CKD trial on Instagram
FIND-CKD on Instagram
A more visual summary of the trial and relevant context (just 6 images to look at!). Infographics by Andreea Manolea
Bonus: more on finerenone in proteinuric CKD universe- visuals by Cristina Popa
TRACK trial on Instagram
TRACK trial on Instagram
A more visual summary of the trial and relevant context (just 6 images to look at!). Infographics by Cristina Popa
MAJESTY trial on Instagram
MAJESTY trial on Instagram
A more visual summary of the trial and relevant context (just 6 images to look at!). Infographics by Cristina Popa
Credit Where Credit is Due
NephJC Book Club 2026: As Long As The Lemon Trees Grow
The NephJC Summer Book Club is back, did you miss us?
Every summer at the NephJC world headquarters we like to slow down and read something a bit longer than a scientific manuscript. And every summer it is the least attended chat of the year.
We’re exploring another fiction title this time. Since the world is currently facing multiple conflicts, we’d like to take you inside one individual’s vision of that dystopia, from the eyes of a young woman who is one of the last remaining medically trained people in her small town. In a world filled with sorrow and sourness can people still find moments of beauty and hope?
As Long as the Lemon Trees Grow by Zoulfa Katouh is a coming of age story set on the background of the Syrian War. Salama once expected to study pharmacy and live an ordinary life. The revolution destroys that future: her mother dies, her father and brother are arrested, and Salama begins treating wounded civilians at an understaffed hospital despite having little practical medical training.
Salama observes, "Death is an excellent teacher."
At home, Salama cares for Layla, her pregnant sister-in-law and closest friend. Salama, however, fears that staying will lead to more death and secretly tries to arrange passage out of Syria. Salama also has visions of Khawf, whose name means fear in Arabic. He pressures her to flee and creates frightening scenarios that intensify her anxiety.
Her life changes when she meets Kenan, a young man committed to documenting the revolution. Kenan films what is happening so the outside world cannot deny the suffering he witnesses firsthand. Through him, Salama rediscovers tenderness, humor, and the possibility of a future.
#NephJC Discussion 9/15/26, Tuesday 9pm EST on Twitter
The book explores many themes that make us human: trauma and survivor’s guilt, home, faith, love as resistance and storytelling. Death around every corner is also another element of this story that draws the reader into the narrator’s sense of urgency and helplessness. The pacing and storytelling emphasize that war is hell, and every day is precious and could be the last. Most importantly, the novel contrasts between living and merely surviving: the possibility of death should not eliminate human connection.
The reader is also invited to question, if your home was being destroyed, would you stay and help or leave and fight another day?
"No one takes to a rickety boat on the sea if there is another choice."
There are twists and turns that cannot be anticipated and may make you audibly gasp. The message is clear: war is terrible, but we should not look away, survivors’ stories need to be told. Often those of us who are far removed from these battlefields cannot comprehend what is taking place on the ground in the ongoing conflicts. This novel help to put a face on those horrors and explores the empathy of the reader for situations that are entirely out of one’s control. As Long as the Lemon Trees Grow is a compelling and emotionally resonant novel that combines historical context, personal struggle, and literary artistry. The narrative also emphasizes loyalty, love, and moral dilemmas, showing how ordinary people navigate extraordinary circumstances.
-Brian Rifkin
Buffering without benefit? The SODa-BIC study
SODa BIC: El Resumen Visual
El bicarbonato quizá no beneficie a todos los pacientes con acidosis metabólica. Tras SODa-BIC, la pregunta ya no es si funciona, sino ¿en qué pacientes podría seguir aportando beneficio?
Revisa el resumen visual creado por Daniel Ramirez #NephJC
SODa BIC: The Visual Abstract
Bicarbonate may not benefit all patients with metabolic acidosis. After SODa-BIC, the question is no longer whether it works, but which patients, might still benefit.
Check out the VA by Daniel Ramirez #NephJC
Finerenone across the proteinuric CKD spectrum
Beyond Diabetic Kidney Disease: FIND-ing Finerenone's Next Role
FIND-CKD extends finerenone beyond diabetic kidney disease, showing slower eGFR decline and sustained albuminuria reduction in non-diabetic CKD. While the benefits are modest and cardiovascular effects remain uncertain, the trial opens the door to broader use of nsMRAs and raises important questions about combination therapy with SGLT2 inhibitors.
FIND CKD: The Visual Abstract
Is finerenone ready to move beyond diabetes?
The FIND-CKD phase 3 arrived from the #ERA26 and is the first one to show kidney protection with finerenone in non-diabetic CKD.
The next challenge is no longer whether finerenone belongs in non-diabetic CKD, but how to best combine with the rest of the pillars to maximize protection.
Check out the newest VA created by our intern Raquel Barba
FIND CKD: El Resumen Visual
¿Está la finerenona lista para ir más allá de la diabetes?
El estudio FIND-CKD recien llegado del #ERA26, es el primer ensayo fase 3 que demuestra protección renal con finerenona en pacientes con ERC no diabética.
El siguiente reto ya no es si la finerenona tiene un lugar en la ERC no diabética, sino cómo combinarla de la mejor manera con el resto de los pilares del tratamiento para maximizar la protección renal.
No se pierdan el nuevo Visual Abstract creado por nuestra interna Raquel Barba
On the right TRACK? Rivaroxaban to prevent cardiovascular events in advanced CKD.
Track: The Visual Abstract
Can rivaroxaban reduce cardiovascular events in advanced CKD?
The TRACK trial compared low-dose rivaroxaban with placebo in patients with stage 4–5 CKD and dialysis-dependent kidney failure at high cardiovascular risk.
Check out the latest VA and review the next #NephJC.
Track: El Resumen Visual
¿Puede rivaroxabán reducir los eventos cardiovasculares en la ERC avanzada?
El estudio TRACK comparó rivaroxabán a dosis bajas frente a placebo en pacientes con ERC estadio 4–5 y enfermedad renal en diálisis con alto riesgo cardiovascular.
Revisa nuestro más reciente resumen visual y acompáñanos en la próxima discusión de #NephJC.
NephJC Short: When BAFF Meets APRIL: Telitacicept in IgA Nephropathy (TELIGAN trial)
Can we predict who benefits from steroids in IgAN? The PRED-IgAN Study
Majesty: The Visual Abstract
Fresh from the #ERA26 Late-Breaking Clinical Trials, the MAJESTY study compared obinutuzumab with tacrolimus and raises important questions about the future of anti-CD20 therapy.
👑 Is deeper B-cell depletion enough to claim the throne?
📖 Check out the latest Visual Abstract by Dr Divya Bajpai