Episode 024: The Filtrate welcomes AKI superstars Jay Koyner and Anitha Vijayan to discuss the recent STARRT trial which is the definitive trial on early versus late start of kidney replacement therapy in AKI.
The Filtrate:
Matt Sparks
Joel Topf
Swapnil Hiremath COI: he was a sub-investigator on STARRT
Jennie Lin
And two special guests:
Dr. Jay Koyner of the University of Chicago and #NephBBQ fame.
Anitha Vijayan, professor of medicine at Wash U in St Louis
Show Notes:
The STARRT-AKI trial acronym is: Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury
Matt suggests STAKRT-AKI Standard versus Accelerated Initiation of Kikdney-Replacement Therapy in Acute Kidney Injury
Coverage at NephJC: Time to Stop Starting RRT Early in AKI
House of God by Samuel Shem. Contemporary Review in the New Yorker. Amazon
Ronco’s legendary dose of CRRT study. Lancet 2000.
AJKD Meta analysis on initiation of dialysis in AKI by VF Seabra.
Timing of Initiation of Dialysis in Critically Ill Patients with Acute Kidney Injury Initiation of dialysis by BUN in the Picard trial by Dr. Kathleen Liu.
AKIKI and ELAIN trials as covered by NephJC
Issues surrounding informed consent in the ICU
Dr Palevsky’s ATN Study, AKA Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury
Debate at Kidney Week: Intensivist vs Nephrologist for Renal Replacement Therapy (RRT) in the ICU
Internal and External Validation of a Machine Learning Risk Score for Acute Kidney Injury
That sweet sweet NephJC pot of gold
Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity
Thai study that used FST to randomize patients for early versus late start KRT: Early versus standard initiation of renal replacement therapy in furosemide stress test non-responsive acute kidney injury patients (the FST trial)
AKIKI 2 at clinical trials.gov
Swapnil’s Tubular secretion, the Twitter timeline of Oded Rechavi
Matt’s Tubular Secretion: #kidneydietchallenge
Anitha comes from the land of coconuts. Lots of potassium in coconut water.
The Skeleton Key Group on The Renal Fellow Network