Our NephJC NOSTONE editorial in Kidney Medicine is live. Great work from Renz Palisan, Nikita Pawar, and Rasha Alawieh; supported by Swap and Jade.
Read it here.
This week, we will discuss a phase 2 trial of the TRPC6 inhibitor BI 764198 in FSGS—an early signal for a podocyte-targeted therapy showing proteinuria reduction but set against small numbers, heterogeneity, and methodological trade-offs that frame this as direction-finding rather than definitive evidence.
This week, we will discuss why a large registry cohort was needed to move past decades of scattered case reports and clarify the true risk of hydralazine‑associated vasculitis. When rare events hide in noise, only scale can reveal the signal. Can population‑level data finally bring this paradox into focus?
Summary of the STEPS trial which will be a twitter spaces discussion
This week, we will discuss the HIT trial- a large randomized study challenging one of the most reflexive responses in hospital medicine: see hyponatremia, fix the sodium. But what if correcting the number doesn’t change what actually matters?
Our NephJC NOSTONE editorial in Kidney Medicine is live. Great work from Renz Palisan, Nikita Pawar, and Rasha Alawieh; supported by Swap and Jade.
Read it here.
Our NephJC STOP-ACEi editorial in Kidney Medicine is live. Great work from Susan Thanabalasingam and Cristina Popa, supported by Nayan, Swap, and Jade.
Read it here.
The NephJC editorial in Kidney Medicine is live. Great work from Sheikh Khalid, Rachel Hung, and William Vasquez Espinosa, supported by Nayan, Joel, and Jamie.
Read it here.
The NephJC editorial in Kidney Medicine is live. Great work from Anand Chellapan and Rachael Kermond, supported by Tiffany, Jade and Swap. Read it here.
With a bonus table which already needs updating post EMPAKIDNEY!
The commentary on the BMJ meta-analysis on PLEX in ANCA vascuitis is now online on Kidney Medicine. Nice work by Anoushka Krishnan, Cristina Popa and Priyadarshini John. Read the paper here
The #NephJC editorial on PATH-BP is now live on Kidney Medicine!
Nice work by Momen Abbasi, Priya John, Cristina Popa, helmed by Jade and Jamie.
The SSASS trial editorial is up in Kidney Medicine! Have a read.
Nice work by Yoshinosuke Shimamura, Michael Turk, Md Abdul Qader and Shweta Shah!
The discussion of the BASICS trial is up at Kidney Medicine. Great work by Mythri Shankar, Carlo Trinidad, and Elliot Tannor. Check it out here.
AURORA-1, the placebo controlled RCT of voclosporin in lupus nephritis is another NephJC discussion that is now available as a Kidney Medicine manuscript. Bourne Auguste, Jade Teakell, and Avinash Rao Ullur did a great job on this. Take a look.
CONFIRM, the placebo controlled RCT of Terlipressin in HRS is another NephJC discussion that is now available as a Kidney Medicine manuscript. Jamie Willows and Alicja Rydzewska-Rosołowska did a great job on this. Take a look.
LANDMARK is the latest NephJC to be converted to a Kidney Medicine Manuscript. Great work by Carlo Nemesio Trinidad, Melisha Hanna and Sharanya Ramesh. Take a look.