Is eculizumab effective in pediatric patients with Shiga toxin-related E. Coli hemolytic uremic syndrome?
Check out the visual abstract by Melvin Chan for the answer.
This week, we will discuss the use of LLMs for the diagnosis of complex nephrology cases. Can AI help nephrologists nail the correct diagnosis?
MERCURI-2 reports that dapagliflozin cuts postoperative AKI after cardiac surgery, but the headline result is mostly a urine-output story, not a creatinine one. That matters: urine output after surgery is easily swayed by anesthesia, fluid shifts, vasopressors, and a diuretic drug in the mix. Until dapagliflozin shows it protects kidney function, not just urine output.
This week, we will discuss SODaBIC trial: with ICU acidosis driven by multiple overlapping mechanisms, is bicarbonate infusion supported by robust evidence, or does it persist mainly out of habit rather than physiology?
FIND-CKD extends finerenone beyond diabetic kidney disease, showing slower eGFR decline and sustained albuminuria reduction in non-diabetic CKD. While the benefits are modest and cardiovascular effects remain uncertain, the trial opens the door to broader use of nsMRAs and raises important questions about combination therapy with SGLT2 inhibitors.
Is eculizumab effective in pediatric patients with Shiga toxin-related E. Coli hemolytic uremic syndrome?
Check out the visual abstract by Melvin Chan for the answer.
Yet another new medication class for use in the RAAS cascade. BI 690517, an aldosterone synthase inhibitor, has been shown to significantly reduce proteinuria with or without empagliflozin. VA by Brian Rifkin.
A very colourful visual abstract from Sabarinath!
Another sterlling visual abstract from Milagros Flores
Check out the beautiful Visual Abstract for this week’s NephJC by Arjun Mohan.
Does natriuresis-guided diuretic therapy in patients with acute heart failure improve clinical outcomes?
NSMC Intern Sameen Aamer answers it with a VA
The kidney cell architecture atlas infographic by Dr Jithu Kurian
Intensive blood pressure control in hospitalized older adults beneficial or detrimental?
NSMC intern Melvin Chan explains with a visual abstract
Is intravenous fluid therapy with a balanced crystalloid solution better than saline for patients receiving a deceased donor kidney transplant? Check out the BEST-FLUID VA by NSMC Intern Anitha Swami
Checkout this VA by NSMC Intern Brammah R. Thangarajah to understand the role of Sodium Thiosulphate in Calciphylaxis
Does bicarbonate retard the progression of kidney allograft failure? check out the visual Abstract by Nyi Min Han
Is Sparsentan effective and safe for patients with IgAN on maximal Raas blockade? Check out the VA by NSMC intern Saumya Vishnoi
Is Rituximab better than azathioprine for maintenance therapy of relapse in ANCA-associated vasculitis? Checkout the RITAZAREM study VA.
Check out the crisp VA on NOSTONE trial by Renz Pasilan
Does testing for coronary heart disease before kidney transplant improve post transplant outcomes? To know the answer check out the beautiful VAs created by NSMC Interns Renz and Nihal!
Does Torsemide lower all cause mortality compared to furosemide for heart failure patients post-hospitalization? Cristina Popa elaborates, visually!
Is Chlorthalidone superior to Hydrochlorothiazide in preventing major adverse cardiovascular events? Here is the VA from Mike Turk
Does Bardoxolone help patients with Alport’s Syndrome? Dr M Abdul Qader explains graphically.