A thread on the most relevant part of the chat on tolerance induction in HLA-matched transplant with donor hematopoietic stem cells (MDR-101). Thread by Akshaya Jayachandran.
Immune tolerance in kidney transplantation: from first principles to clinical engineering
Tolerancia inmunológica: ¿la quimera del trasplante renal? - El resumen visual
¿Qué significa estar libre de inmunosupresión en el trasplante renal?
Revisa el Resumen Visual por Bogdan Agavriloaei
Achieving immune tolerance by chimerism in kidney transplant
Is getting immunosuppression-free a chimera in kidney transplant?
Check out the visual abstract by Bogdan Agavriloaei
Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?
Microvascular inflammation of kidney allografts
Microvascular inflammation from the perspective of a real unicorn: donor-specific antibodies with negative antibody mediated rejection 🦄
Kidney Allografts-Play With Fire, Get Burned
Playing It Safe: Can Felzartamab Fill the Gap in AMR Treatment?
The Balance of Giving: Understanding Risks for Living Kidney Donors
🤔 Hypothermia or machine perfusion for kidney transplant?
Hypothermia or Machine Perfusion in Kidney Donors (Malinoski, NEJM 2023)
🤔 Precision diagnostics of kidney allograft biopsies
An automated histological classification system for precision diagnostics of kidney allografts (Yoo, Nature Medicine 2023)
Unlocking the door to living kidney donor paradise?
This week, nephrologists hope they found the key to no-dialysis-land, where kindness and detailed, multistep interventions make the path to kidney transplant much easier. This was foreseen in our Freely Filtered episode and disputed during #KidneyWK 2023 late-breaking clinical trials session. Still, when it comes to RCTs’ results, will it be Deja Vu or a happy ending?
Fluid Wars: Plasmalyte Strikes Back
Patients are given a lot of fluid post-transplant, but which to choose? Catch up on the latest evidence here.
Art of Balance In Preventing Delayed Graft Function - BEST FLUIDS for better outcomes
Giving oral bicarb raises serum bicarb
RCT of PO sodium bicarbonate in patients with renal transplant to see if impacts stability of renal function - catch up here!
A litmus test: Does Sodium Bicarbonate Prevent Graft Function Decline?
TenTweet summary - cardiac testing prior to kidney transplant
It’s a controversial topic: click below to catch-up
Visual Abstract for Pre-Transplant Workup
Does testing for coronary heart disease before kidney transplant improve post transplant outcomes? To know the answer check out the beautiful VAs created by NSMC Interns Renz and Nihal!
Behind the Screen: Cardiac testing before Kidney Transplantation
What is dd-cfDNA and how might it help?
Read the #TenTweetNephJC summary of the ADMIRAL study, examining how dd-cfDNA monitoring may help us manage our patients with renal transplants.