Background
swapnil hiremath
Double Trouble: ddAVP and the Bleeding Biopsy

This week, we will discuss a double header: two single centre ddAVP trials in kidney biopsy from India.

Double Trouble: ddAVP and the Bleeding Biopsy
Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review
Background
Cristina Adriana Popa
REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨

REGENCY: A B-Cell Super Destroyer in Lupus

cristina popa

Desmopresina intranasal: ¿previene el sangrado tras la biopsia renal en pacientes con enfermedad renal crónica?

Y no, no estás viendo doble… Doble dosis de desmopresina en #NephJC. El segundo estudio de Chakrabarti et al incluyó un escenario más complejo, aunque con resultados no concluyentes.

¿Será momento de replantear los estudios con desmopresina en la vida real?

No olvides revisar el resumen visual creado por Cristina Popa.

Metformina en la ERC avanzada

Un estudio observacional con emulación de ensayo aleatorizado en Escocia sugiere que mantener metformina en pacientes con ERC estadio 4 se asocia con mejor supervivencia y sin aumento de eventos cardiovasculares adversos mayores 🫀.

¿Estamos listos para replantear esta práctica?

Aquí te dejamos el resumen visual por Cristina Popa #NephJC

REGENCY: A B-Cell Super Destroyer in Lupus

REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨

Hunting Primary Hyperaldosteronism: are MRAs a blindfold in adrenal vein sampling?

Hunting Primary Hyperaldosteronism: are MRAs a blindfold in adrenal vein sampling?

This week, we will continue with February’s aldosterone leitmotif: do mineralocorticoid receptor antagonists (MRAs) truly blind the diagnostic in unilateral hypraldosteronism? Is this the article the mythbuster? Draw your own conclusions

Hungry Like The Wolf for New Lupus Nephritis Guidance

Hungry Like The Wolf for New Lupus Nephritis Guidance

This week, we will discuss the recently published KDIGO lupus guidelines. Published a couple of years after the big GN guidelines - let us dive in to see what’s new in lupus nephritis

Fluid Wars: Plasmalyte Strikes Back

Patients are given a lot of fluid post-transplant, but which to choose? Catch up on the latest evidence here.

Antibiotics and sudden cardiac death: #NephJC Tweetorial Catch-up

Which antibiotics increase risk of sudden death in your patient on haemodialysis? Probably something you should know. Check out our rapid-fire summary tweetorial at the link!