Background
swapnil hiremath
Double Trouble: ddAVP and the Bleeding Biopsy

This week, we will discuss a double header: two single centre ddAVP trials in kidney biopsy from India.

Double Trouble: ddAVP and the Bleeding Biopsy
Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review
Background
Cristina Adriana Popa
REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨

REGENCY: A B-Cell Super Destroyer in Lupus

tweetorial

More options for immunosuppression in IgA....

Check out the tweetorial for the MAIN event - does MMF work in IgA Nephropathy?

TenTweet summary - cardiac testing prior to kidney transplant

It’s a controversial topic: click below to catch-up

Confusing AF

Now that twitter has recovered from its downtime, a catch-up tweetorial on apixaban for AF in patients on dialysis for you.

Water, Water Everywhere: The Diuretic Wars Continue!

What’s your loop and thiazide of choice? Do you know which diuretics are better, faster, stronger? This week’s TenTweets is a two-fer (Chlorthalidone vs HCTZ and Furosemide vs Torsemide). Tweetorial catch-up here.

IgA and steroids: the saga continues

Drug reps pitching you Nefecon? Catch-up with the RCT in our #TenTweetNephJC tweetorial

Checking in on MyTEMP - #TenTweetNephJC

The last NephJC of the year brought us a cool discussion on if cooling dialysate could help mitigate the effects of intradialytic hypotension. Get caught up with the chat in the latest edition of #TenTweetNephJC.

New player in resistant hypertension?

This week we discussed aprocitentan, another endothelin receptor antagonist, this time being explored in the resistant hypertension arena - you know the #TenTweetNephJC drill, if you want a rapid catch up then here’s your place!

Don't Stop Me Now!

If you missed the latest NephJC discussion, at least read the highlights here.

You gotta know when to hold’em and know when to fold’em. Review the #TenTweetNephJC for the STOP ACEi Trial, and always hold onto your ACEi.


Flozins strike again!

If you missed the biggest NephJC of the year, at least read the highlights here.

The future for refractory lupus nephritis?

Ten Tweet round up of exciting CAR T trial in patients with SLE discussed last month - check it out while you can!

What does the future look like in ADPKD?

Basic science week - catch up in only Ten Tweets here.

More diuretics = more diuresis

The ADVOR trial (adding acetazolamide in acute heart failure) is covered by #TenTweetNephJC

Is piperacillin-tazobactam nephrotoxic?

The debate continues, but this time with cystatin-C measurements. Read the #TenTweetNephJC summary here!

Speak volumes: #TenTweetNephJC wrap-up on CLASSIC

Intravenous fluids in sepsis - not exactly a rare treatment in a niche condition. Rapidly catch-up on this weeks journal club at the link for the take-home points.

SODIUM-HF: removing 'strict' from 'restriction'

If you missed out of the great #NephJC chat this week you can catch-up with our rapid 10 tweet summary.

Antibiotics and sudden cardiac death: #NephJC Tweetorial Catch-up

Which antibiotics increase risk of sudden death in your patient on haemodialysis? Probably something you should know. Check out our rapid-fire summary tweetorial at the link!

What is dd-cfDNA and how might it help?

Read the #TenTweetNephJC summary of the ADMIRAL study, examining how dd-cfDNA monitoring may help us manage our patients with renal transplants.

Ten Tweets does TESTING 2.0

Did you miss the TESTING reboot discussion? No worries, we have you covered here: