Brian Rifkin

December 20, 2025

tweetorial

TenPosts LIBERATE-D

Brian Rifkin

December 20, 2025

tweetorial

Is less actually more when trying to liberate patients with AKI on dialysis? Read the summary 10 posts and find out

swapnil hiremath

December 17, 2025

NephJC Shorts

BigPAK or a bundle of balderdash?

swapnil hiremath

December 17, 2025

NephJC Shorts

We break down the latest salvo from Zarbock et al on a supposedly wonderful ‘bundle’

Brian Rifkin

December 15, 2025

Background

Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D

Brian Rifkin

December 15, 2025

Background

Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D

This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.

swapnil hiremath

August 5, 2024

Background

Trial by Combat: Do Amino Acids provide PROTECTION to the Kidneys?

swapnil hiremath

August 5, 2024

Background

Trial by Combat: Do Amino Acids provide PROTECTION to the Kidneys?

This week, we will discuss an intriguing hypothesis for many nephrologists: can amino acids prevent acute kidney injury?

Cristina Adriana Popa

June 24, 2024

Background

Heart-burn and Kidney Churn

Cristina Adriana Popa

June 24, 2024

Background

This week, we will maybe not expect the worse, while discussing the COMPASS post hoc analysis. Are PPIs so bad for the kidneys?

joel topf

February 5, 2024

Future Topic

🤔 Risk of AIN with PPI/ICI overstated

joel topf

February 5, 2024

Future Topic

Proton pump inhibitors and the risk of acute kidney injury in cancer patients receiving immune checkpoint inhibitors: A Danish population-based cohort study (Munch, International Journal of Cancer 2023)

joel topf

February 5, 2024

Future Topic

🤔 E-alerts in AKI, the ELAIA-2 trial

joel topf

February 5, 2024

Future Topic

A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes (Wilson, Nature Communications 2023)

joel topf

February 5, 2024

Future Topic

🤔 RCT comparing Cefepime with Pip/Taz and AKI

joel topf

February 5, 2024

Future Topic

Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial (Quian, JAMA 2023)

Jade Teakell

August 21, 2023

Background

CXCL9: A Urinary Marker ExplAINed

Jade Teakell

August 21, 2023

Background

What do you do when you suspect AIN (and eosinophils aren’t helpful) and you can’t get a kidney biopsy? CXCL9 is a newly discovered urinary marker that may help in the diagnosis of AIN. This week we will discuss the process of isolating and utilizing this new diagnostic test.

Guest User

September 20, 2022

tweetorial

Is piperacillin-tazobactam nephrotoxic?

Guest User

September 20, 2022

tweetorial

The debate continues, but this time with cystatin-C measurements. Read the #TenTweetNephJC summary here!

Welcome to #TenTweetNephJC tweetorial

✳️ 10 tweets to catch-up with #NephJC ✳️

Have you ever prescribed piperacillin-tazobactam? Or avoided it due to fear of causing AKI?

Read on to learn more about the ‘nephrotoxin’ versus ‘pseudonephrotoxin’ debate pic.twitter.com/ZKX1ElhZds
— Nephrology Jrnl Club (@NephJC) September 13, 2022

swapnil hiremath

September 6, 2022

Background

Vancomycin and Piperacillin-Tazobactam: Friends or foes?

swapnil hiremath

September 6, 2022

Background

Vancomycin and Piperacillin-Tazobactam: Friends or foes?

Pip/Tazo and Vanco is the new new kid on the block for antibiotic induced AKI. Does it deserve its bad boy reputation?

Guest User

March 23, 2021

Background

Spin the Urine! Then Spin it Again!

Guest User

March 23, 2021

Background

This week we’ll be discussing a Kidney 360 paper validating two recent methods of prognostication of AKI by evaluation of the urine sediment.

swapnil hiremath

January 26, 2021

Background

Alerting AKI and Avoiding Adverse Aftermaths

swapnil hiremath

January 26, 2021

Background

Alerting AKI and Avoiding Adverse Aftermaths

This week we discuss the AKi Alert trial from BMJ. Surely alerting us to AKI earlier will be helpful, right? Maybe - or maybe not. Join us to discuss this very important trial with some counter intuitive results.

swapnil hiremath

August 4, 2020

Background

Time to Stop Starting RRT Early in AKI

swapnil hiremath

August 4, 2020

Background

This week, we will discuss the fresh-off-the-press STARRT AKI trial. The final, definitive trial to let us know about the timing of KRT in the ICU.

swapnil hiremath

November 25, 2019

Background

Repurposing old drugs: Mannitol for Intradialytic Hypotension

swapnil hiremath

November 25, 2019

Background

Repurposing old drugs: Mannitol for Intradialytic Hypotension

This week, we will discuss a pilot trial of using mannitol to treat intradialytic hypotension. A daily occurence in our practice, hence providing some much needed data.

swapnil hiremath

September 24, 2019

Commentary

The Rise and Rise of Quantitative Cassandras

swapnil hiremath

September 24, 2019

Commentary

The Rise and Rise of Quantitative Cassandras

Saurabh Jha aka @RogueRad comments on the AI predicting AKI paper. There are trade offs involved in predicting events before they occur. Especially if they do not occur. Clear enough? If not, dive in to read more…

swapnil hiremath

March 19, 2019

Background

Newsflash: Numerous NSAIDs are Nephrotoxic

swapnil hiremath

March 19, 2019

Background

Newsflash: Numerous NSAIDs are Nephrotoxic

Its March. Which means it is NephMadness.

In conjunction with NephMadness - Pain Region discussion, we discuss a recent JAMA Network Open study, reporting higher kidney risk in young men taking NSAIDs.

swapnil hiremath

November 11, 2018

Background

There's just been AKI. So what do we do with the ACEi/ARB?

swapnil hiremath

November 11, 2018

Background

There's just been AKI. So what do we do with the ACEi/ARB?

There is AKI. You are ready to discharge the patient. Should you restart their ACEI/ARB? Or they were never on an ACEI/ARB - but surely with a history of heart failure, they should be on one? How do you decide? Join us to discuss some exciting new data

swapnil hiremath

July 7, 2018

Background

RELIEF: More Fluids mean Less AKI?

swapnil hiremath

July 7, 2018

Background

Randomized controlled trial of restrictive versus liberal IV fluid strategy around abdominal surgery.

swapnil hiremath

March 10, 2018

Background

The Fluid Wars Return: Can we restore Balance to the field

swapnil hiremath

March 10, 2018

Background

The Fluid Wars Return: Can we restore Balance to the field

March 13/14 we will discuss the pair of trials in NEJM from Vanderbilt: comparing balanced solutions to normal saline in critically ill & not ill patients. Join us for the next #NephJC to parse through SMART & SALT-ED