Hypertension Collection

This is Cristina’s Idea

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PRAECISely Predicting Preeclampsia
PRAECISely Predicting Preeclampsia

This week, we tag along with NephMadness. It will be hard to stay impartial while discussing the role of angiogenic and antiangiogenic factors in severe preeclampsia prognosis.

Pressure! Pushing down on me, pushing down on you: Should we be aggressively treating inpatient hypertension?
Pressure! Pushing down on me, pushing down on you: Should we be aggressively treating inpatient hypertension?

Classic scenario: young doctor, old patient with asymptomatic hypertension…
This week we are going against our instinct to normalize blood pressure numbers and listening to our wise elders.

PRECISION Targeting in Resistant Hypertension
PRECISION Targeting in Resistant Hypertension

This week, we will discuss the first new BP lowering drug in decades. Aprocitentan, a dual endothelin antagonist in a meticulously designed trial in resistant hypertension.

A New CHAPter in an Old Story
A New CHAPter in an Old Story

This week, we have a practice changing study about the treatment of mild hypertension during pregnancy. Join us on Tuesday (9 EDT) and Wednesday (9 IST).

Pain, Paracetamol and Pressure
Pain, Paracetamol and Pressure

This week, we will discuss the PATH BP trial, which demolishes the supposed benign nature of acetaminophen/paracetamol.

Old is Gold: CLICK for Chlorthalidone
Old is Gold: CLICK for Chlorthalidone

This week, we will discuss the CLICK trial. Another medical reversal - showing that this old and cheap drug, chlorthalidone, might actually work in advanced CKD. Click through to read more.

The Na-K Exchange Saves Lives
The Na-K Exchange Saves Lives

This week, we will discuss the SSASS trial. in which a simple switch of table salt with a K-enriched salt works miracles. Is it about the sodium or the potassium?

Diagnosing Aldosteronism
Diagnosing Aldosteronism

This week, we will discuss the correct way to diagnose primary aldosteronism. Is a spot ARR sufficient? Prepare to turn whatever you thought you knew about PA around.

Patiromer, spironolactone and resistant hypertension.
Patiromer, spironolactone and resistant hypertension.

The new generation of potassium binders bind potassium but can they improve patient outcomes? These second order questions are starting to be answered. Join us this week to discuss the use of patiromer and spironolactone in patients with resistant hypertension.The AMBER Study

Is Renal Denervation Innervated Again?
Is Renal Denervation Innervated Again?

Check out the overall summary of all our renal denervation trial bonanza from 2018.

RADIANCE SOLO: Denervation with a Difference?
RADIANCE SOLO: Denervation with a Difference?

This is the summary of the RADIANCE SOLO trial, of renal denervation using an intravascular ultrasound, in patients not on medications.

SPYRAL ON: Renal Denervation in Patients ON Medications
SPYRAL ON: Renal Denervation in Patients ON Medications

This is the summary of the SPYRAL HTN-ON trial - of renal denervation in patients on 1-3 medications.

SPYRAL OFF: Can Renal Denervation Reduce Blood Pressure in Hypertension?
SPYRAL OFF: Can Renal Denervation Reduce Blood Pressure in Hypertension?

This is the summary of one of the three RDN trials we are discussing - SPYRAL HTN-OFF, which examined the effect of renal denervation in patients with mild hypertension, who were off medications.

Renal Denervation: the Story so far...
Renal Denervation: the Story so far...
#NephJC next week: Renal Denervation Bonanza
#NephJC next week: Renal Denervation Bonanza

Next Tuesday and Wednesday we will discuss three, yes, three trials of renal denervation. Is renal denervation ready to rise, phoenix-like, from the ashes of Symplicity-3?

Haircutting Hypertension: Barbers & Blood Pressure
Haircutting Hypertension: Barbers & Blood Pressure

This week, we will discuss the NEJM cluster RCT from Victor and colleagues, which has created such a buzz. Barbers and pharmacists team to have a fantastic effect. Could it be true? 

Is 130 the new 140? The 2017 AHA/ACC Hypertension guidelines
Is 130 the new 140? The 2017 AHA/ACC Hypertension guidelines

Join us as we dissect a few key aspects of the mammoth undertaking that was the 2017 ACC/AHA blood pressure guidelines!

Hypertension Guidelines: Managing Blood Pressure in kids and teenagers
Hypertension Guidelines: Managing Blood Pressure in kids and teenagers

Join us this week as we discuss guidelines - with a difference. Hypertension, but in children - as the AAP unveiled them recently. The entire manuscript is over 70 pages, so make sure you read this succinct summary from Cathy Quinlan.  
Spironolactone primer