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NephJC

Queue
Flozinator
Blog
Podcasts
Freely Filtered
RoboPod
Channel Your Enthusiasm
More
Club de Articulos
Code of Conduct
The Why, When and How
The NephJC Organization
Twitter Journal Club Primer
Who are we
Masthead
COVID19
Seminars in Nephrology
Regarding Twitter...
Newsletter
October 27, 2025
Background
Cristina Adriana Popa
2025 IgAN KDIGO guidelines: fresh out of ...

This week, we will discuss the 2025 KDIGO IgAN guidelines. which the shift from supportive care to structured, evidence-based therapy

 2025 IgAN KDIGO guidelines: fresh out of press, already aging gracefully
October 13, 2025
Background
Cristina Adriana Popa
The Protein Pendulum in CKD: supplement or ...

This week, we will discuss an old dilemma in nephrology. To restrict or supplement the proteins? Premise: advanced CKD and dialysis.

The Protein Pendulum in CKD: supplement or restrict?
September 28, 2025
Background, summary
Brian Rifkin
Chimerism and Immune Tolerance: Can We Says ...

This week, we will discuss the use of creating chimeras to induce immune tolerance and its potential to decrease or eliminate the need for immunosuppression in kidney transplant recipients.

Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?
September 21, 2025
Meta
joel topf
NephJC 2025 Fall Pledge Drive

Help keep NephJC a vital, original, and unbiased source of medical education.

NephJC 2025 Fall Pledge Drive
September 15, 2025
Background, summary
Brian Rifkin
PREVENT, Detect, Treat: What’s New in the 2025 ...

This week, we will discuss the AHA/ACC 2025 hypertension guideline update. Wow, have eight years flown by?

PREVENT, Detect, Treat: What’s New in the 2025 Hypertension Toolkit
swapnil hiremath
December 7, 2021
Background

Old is Gold: CLICK for Chlorthalidone

swapnil hiremath
December 7, 2021
Background
Old is Gold: CLICK for Chlorthalidone

This week, we will discuss the CLICK trial. Another medical reversal - showing that this old and cheap drug, chlorthalidone, might actually work in advanced CKD. Click through to read more.

Tagged: aarthi, chlorthalidone, hypertension, nejm, trial, rct, positive, click, agarwal, ckd, blood pressure

joel topf
November 23, 2021
Commentary

The AQP1 Visual Abstract

joel topf
November 23, 2021
Commentary

Nice visual abstract on this week’s NephJC by Abdul Qader

Tagged: visual abstract, Visual Abstract, aquaporin, aqp1, peritoneal dialysis

joel topf
November 23, 2021
Background

Genes, Aquaporins, and Peritoneal Dialysis

joel topf
November 23, 2021
Background
Genes, Aquaporins, and Peritoneal Dialysis

This week, we discuss the discovery that peritoneal membrane water transport, and PD outcomes, are influenced by genetic variations in the Aquaporin 1 channel.

Tagged: nejm, positive, aqp1, peritoneal dialysis, Water, observational, Michael Turk, aquaporin, gwas

joel topf
November 20, 2021
Meta

The 2021 NephJC Kidneys Official Ballot

joel topf
November 20, 2021
Meta
The 2021 NephJC Kidneys Official Ballot

Here is the official 2021 NephJC Kidneys Ballot

Tagged: nephjckidneys, nephjc kidneys

Guest User
November 16, 2021
Commentary

2021 KDIGO Updates for Glomerular Disease: The Visual Abstract

Guest User
November 16, 2021
Commentary

This update was too big for just one slide! Michael Turk produced two Visual Primers to help you understand the 2021 GN changes at-a-glance.

Tagged: Michael Turk, KDIGO, Glomerulonephritis, visual abstract, kdigo-gn, kdigo, glomerulonephritis, Visual Abstract

swapnil hiremath
November 16, 2021
Background

The 2021 KDIGO GN Guidelines

swapnil hiremath
November 16, 2021
Background
The 2021 KDIGO GN Guidelines

This week, we will discuss the updated 2021 GN guidelines from KDIGO. They have always been the most useful of all GN guidelines. Let’s see what has changed

Tagged: kdigo, kdigo-gn, guideline, guidelines, shweta, kidney international, sle, lupus nephritis, mcd, membranous, IgA Nephropathy, c3gn

joel topf
November 12, 2021
Meta

The NephJC Kidneys...nominations close next Wednesday

joel topf
November 12, 2021
Meta
The NephJC Kidneys...nominations close next Wednesday

Time to nominate people for the 2021 NephJC Kidneys

Tagged: nephjc kidneys, nephjckidneys, prize, cjasn, social media

joel topf
November 7, 2021
Meta

Delay of game. KDIGO GN discussion pushed back to next week.

joel topf
November 7, 2021
Meta

Due to Kidney Week, grant deadlines, and a general inability to get it together, we are postponing the KDIGO GN chat until November 16, 17. Sorry….Not sorry.

Tagged: kidgo-gn

joel topf
October 31, 2021
Meta

The NephJC Kidneys...late but not forgotten.

joel topf
October 31, 2021
Meta
The NephJC Kidneys...late but not forgotten.

Time to nominate people for the 2021 NephJC Kidneys

Tagged: nephjc kidneys, nephjckidneys, prize, cjasn, social media

joel topf
October 26, 2021
Commentary

A SSaSSy Visual Abstract

joel topf
October 26, 2021
Commentary

shweta shah did an amazing job on this week’s visual abstract.

Tagged: visual abstract, ssass, shweta

swapnil hiremath
October 25, 2021
Background

The Na-K Exchange Saves Lives

swapnil hiremath
October 25, 2021
Background
The Na-K Exchange Saves Lives

This week, we will discuss the SSASS trial. in which a simple switch of table salt with a K-enriched salt works miracles. Is it about the sodium or the potassium?

Tagged: sodium, potassium, blood pressure, hypertension, nejm, trial, rct, positive, yoshinosuke, ssass

swapnil hiremath
October 11, 2021
Commentary

The New GFR Equations in a Picture

swapnil hiremath
October 11, 2021
Commentary

The new equation paper is really difficult to summarize in a visual abstract, but Shimamura Yoshinosuke made an excellent effort

Tagged: visual abstract, Visual Abstract, gfr, egfr, race, race and gfr, new gfr equation, yoshinosuke

swapnil hiremath
October 11, 2021
Background

Time for some new Equations

swapnil hiremath
October 11, 2021
Background
Time for some new Equations

This week, we will discuss the hot off the press. On the quest to solve the disparity created by GFR calculations, we discuss the new equations. Is it time to drop the race coefficient, or is it time to drop serum creatinine entirely?

Tagged: race and gfr, race, new gfr equation, gfr, nejm, observational, ckd-epi, slattery, topf, hiremath

swapnil hiremath
October 9, 2021
Commentary

Race, Ancestry, and GFR: A commentary

swapnil hiremath
October 9, 2021
Commentary
Race, Ancestry, and GFR: A commentary

A commentary on Race and GFR equations from Raj Mehta

Tagged: commentary, race and gfr, race, gfr, raj mehta, new gfr equation

swapnil hiremath
September 25, 2021
news

Introducing Kidney Medicine NephJC Editorials

swapnil hiremath
September 25, 2021
news
Introducing Kidney Medicine NephJC Editorials

Watch for the NephJC editorials in Kidney Medicine.

Tagged: kidney medicine, meta

joel topf
September 21, 2021
Commentary

COVID-19 Monoclonal Antibody Visual Abstract

joel topf
September 21, 2021
Commentary

Carlo Trinidad did an amazing job on this week’s visual abstracts.

REGN-COV2.png

And bonus image!

Tagged: vaccine, visual abstract, carlo trinidad

swapnil hiremath
September 21, 2021
Background

COVID-19 and Vaccines and mABs, Oh My!

swapnil hiremath
September 21, 2021
Background
COVID-19 and Vaccines and mABs, Oh My!

This week, we discuss Vaccines for SARS-COV2 as well as monoclonal antibodies for the pandemic.

Tagged: sars, covid19, vaccine, monoclonal antibodies, carlo trinidad, missy hanna

swapnil hiremath
September 13, 2021
Background

Run-in periods in clinical trials: What can we ACHIEVE?

swapnil hiremath
September 13, 2021
Background
Run-in periods in clinical trials: What can we ACHIEVE?

After cluster RCTs and pragmatic trials, we will discuss the role of run in periods and what we try to achieve by having them in clinical trials. Read on.

Tagged: manasi, nephtrials, Stats, spironolactone, achieve, run-in period, stats

Guest User
September 7, 2021
Commentary

The BaSICS Trial: Visual Abstract

Guest User
September 7, 2021
Commentary

Fabulous VA by Carlo Trinidad for this week’s NephJC on “The BaSICS Randomized Clinical Trial”

Tagged: visual abstract, Carlo Trinidad, Intravenous Fluid, Balanced Solution, 0.9% Saline Solution, The BaSICS, basics trial, Visual Abstract

Guest User
September 7, 2021
Background

BaSICS brings balance to the fluid wars

Guest User
September 7, 2021
Background
BaSICS brings balance to the fluid wars

This week, we will discuss the BaSICS trial which throws a wrench in the recent dogma regarding the superiority of balanced solutions over normal saline for resuscitation.

Tagged: rct, trial, negative, brazil, jama, balanced, balanced solution, basics trial, carlo trinidad

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