trial

Beyond Diabetic Kidney Disease: FIND-ing Finerenone's Next Role

Beyond Diabetic Kidney Disease: FIND-ing Finerenone's Next Role

FIND-CKD extends finerenone beyond diabetic kidney disease, showing slower eGFR decline and sustained albuminuria reduction in non-diabetic CKD. While the benefits are modest and cardiovascular effects remain uncertain, the trial opens the door to broader use of nsMRAs and raises important questions about combination therapy with SGLT2 inhibitors.

On the right TRACK? Rivaroxaban to prevent cardiovascular events in advanced CKD.

On the right TRACK? Rivaroxaban to prevent cardiovascular events in advanced CKD.

Can rivaroxaban improve cardiovascular outcomes in patients with advanced CKD.? Although vascular inflammation and thrombosis are at the heart of CV damage, anticoagulants have not previously shown benefits in CVD patients.

Majesty: The Visual Abstract

Fresh from the #ERA26 Late-Breaking Clinical Trials, the MAJESTY study compared obinutuzumab with tacrolimus and raises important questions about the future of anti-CD20 therapy.

👑 Is deeper B-cell depletion enough to claim the throne?

📖 Check out the latest Visual Abstract by Dr Divya Bajpai

Majesty: El Resumen Visual

Recién llegado desde #ERA26, el estudio MAJESTY comparó obinutuzumab frente a tacrolimus y plantea importantes interrogantes sobre el futuro de las terapias anti-CD20 en la nefropatía membranosa primaria.

👑 ¿Será suficiente una depleción más profunda de células B para reclamar el trono?

📖 Revisa el más reciente resumen visual elaborado por la Dra Divya Bajpai

Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?

Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?

This week, we will discuss the use of creating chimeras to induce immune tolerance and its potential to decrease or eliminate the need for immunosuppression in kidney transplant recipients.

REGENCY: A B-Cell Super Destroyer in Lupus

REGENCY: A B-Cell Super Destroyer in Lupus

This week, we will celebrate in advance World Kidney Day by discussing the results of OBInutuzumab in active lupus nephritis. The LUNAR trial (rituximab versus placebo) was “almost” positive, but not quite there. Would Obi overpower its cousin ritux? ✨