Background

Why-dralazine?! Population risk of drug induced vasculitis

Why-dralazine?! Population risk of drug induced vasculitis

This week, we will discuss why a large registry cohort was needed to move past decades of scattered case reports and clarify the true risk of hydralazine‑associated vasculitis. When rare events hide in noise, only scale can reveal the signal. Can population‑level data finally bring this paradox into focus?

Searchin’ For My Lost Shaker of Salt- Targeted Treatment of Hyponatremia

Searchin’ For My Lost Shaker of Salt- Targeted Treatment of Hyponatremia

This week, we will discuss the HIT trial- a large randomized study challenging one of the most reflexive responses in hospital medicine: see hyponatremia, fix the sodium. But what if correcting the number doesn’t change what actually matters?

Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?

Chimerism and Immune Tolerance: Can We Says Goodbye to Immunosuppression?

This week, we will discuss the use of creating chimeras to induce immune tolerance and its potential to decrease or eliminate the need for immunosuppression in kidney transplant recipients.

#NephJC Summer Bookclub: Everything is Tuberculosis by John Green

#NephJC Summer Bookclub: Everything is Tuberculosis by John Green

The summer book club started in 2015, with one of the best books we have done in book club, Atul Gawande's Being Mortal. I think it should be required reading for all physicians. So now, in 2025, it is the NephJC Summer Book’s tenth anniversary (which represents our eleventh book). The history has been rich: