JASN

Does Contrast cause acute Kidney Injury?

Does Contrast cause acute Kidney Injury?

Iodinated contrast is well known to cause acute kidney injury (AKI), mainly from its physico-chemical properties, and is the commonly cited as being the third most common cause of AKI in hospitalized patients. But is this really true? Even the term contrast-induced AKI (CI-AKI) is now being increasingly replaced by contrast-associated AKI (CA-AKI), and could contrast be an 'innocent bystander'?