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NephJC

Queue
Flozinator
Blog
Podcasts
Freely Filtered
RoboPod
Channel Your Enthusiasm
More
Club de Articulos
Code of Conduct
The Why, When and How
The NephJC Organization
Twitter Journal Club Primer
Who are we
Masthead
COVID19
Seminars in Nephrology
Regarding Twitter...
Newsletter
August 18, 2025
Background
joel topf
#NephJC Summer Bookclub: Everything is ...

The summer book club started in 2015, with one of the best books we have done in book club, Atul Gawande's Being Mortal. I think it should be required reading for all physicians. So now, in 2025, it is the NephJC Summer Book’s tenth anniversary (which represents our eleventh book). The history has been rich:

#NephJC Summer Bookclub: Everything is Tuberculosis by John Green
August 4, 2025
Background
Cristina Adriana Popa
High or Low Phosphate? Are we Missing the ...

This week, we will discuss the phosphate targets in dialysis. Are you aiming for HIgh or Low?

High or Low Phosphate?  Are we Missing the (P)oint?
July 21, 2025
Background
Brian Rifkin
Mind The Gap: When eGFR Creatinine and Cystatin ...

This week, we will discuss the clinical significance of eGFRdiff, the difference in eGFRcys (cystatin C) and eGFRcr (creatinine).

Mind The Gap: When eGFR Creatinine and Cystatin C Disagree
July 7, 2025
Background
Cristina Adriana Popa
A dose of CONFIDENCE: Building evidence for ...

This week, we will discuss how the CONFIDENCE trial gets nephrology closer to the magic CKD polypill of CKD.

A dose of CONFIDENCE: Building evidence for finerenone-empagliflozin synergy in diabetic kidney disease
June 25, 2025
Background
swapnil hiremath
From single shots to strategy: How CAPTIVATE is ...

Summary of the CAPTIVATE platform which will be a twitter spaces discussion

From single shots to strategy: How CAPTIVATE is reframing the NephTrials playbook
joel topf
March 24, 2020
news

DIALYSIS and CKD

joel topf
March 24, 2020
news
DIALYSIS and CKD

The NephJC team is working to gather the most up to date and accurate information on how to do chronic dialysis in the middle of the pandemic.

Tagged: coronakidney, covid19, hemodialysis, dialysis

swapnil hiremath
March 21, 2020
Commentary, news

Byrd's Words: Preprints and Peer Review

swapnil hiremath
March 21, 2020
Commentary, news
Byrd's Words: Preprints and Peer Review

What is a preprint anyway? And how is it different from a ‘real’ research paper. What about reviews or perspectives?

Brian Byrd breaks it down for us

Tagged: preprints, Meta, byrd, byrdswords, covid-19

swapnil hiremath
March 21, 2020
Commentary, news

ACUTE KIDNEY INJURY

swapnil hiremath
March 21, 2020
Commentary, news
ACUTE KIDNEY INJURY

As with all the other pages on COVID-19 here on NephJC, this page on AKI & the discussion are not meant to be treatment recommendations based on sound evidence. Our aim on this page is to merely discuss the science of what we know, and some of the biology and mechanisms as well as practical management aspects.

Tagged: covid19, coronakidney, AKI, hiremath, jennie lin, covidaki

swapnil hiremath
March 14, 2020
news

ACE2 and HYPERTENSION

swapnil hiremath
March 14, 2020
news
ACE2 and HYPERTENSION

There has been an unprecedented interest in this topic. Hence we have added more details and moved this section from the main page to a dedicated area with focus on hypertension and ACE2. Curated by Matt Sparks and Swapnil Hiremath, with additional expert input from the COVID-ACE2 workgroup

Tagged: covid19, coronakidney, sars, ace, ace2, hypertension, sparks, hiremath, Hypertension, blood pressure

swapnil hiremath
March 10, 2020
Commentary

ISPD 2020 Recommendations: Dr Liew's Take

swapnil hiremath
March 10, 2020
Commentary
ISPD 2020 Recommendations: Dr Liew's Take

Adrian Liew, one of the principal authors of the new ISPD guidelines on (don’t say adequacy) high-quality goal-directed peritoneal dialysis shares his thoughts on what makes these guidelines unique and ground breaking.

Tagged: ispd, ispd2020, peritoneal dialysis

swapnil hiremath
March 10, 2020
Commentary

ISPD 2020 Recommendations: A Patient Commentary

swapnil hiremath
March 10, 2020
Commentary
ISPD 2020 Recommendations: A Patient Commentary

Steve Quinlan is a patient who did PD for a year. He looked at the 2020 ISPD guidelines of adequacy and he has thoughts…

Tagged: patient voice, Patient Voice, Quinlan, ispd, ispd2020, guidelines, peritoneal dialysis

swapnil hiremath
March 9, 2020
Commentary

ISPD 2020 Recommendations: The Visual Abstract

swapnil hiremath
March 9, 2020
Commentary

It is hard to do a visual abstract for guidelines.

But nothing’s too hard for NSMC graduate and now faculty, Krithika Mohan aka @krithicism

Tagged: ispd, ispd2020, visual abstract, Visual Abstract, krithika

Guest User
March 9, 2020
Background

ISPD Practice Recommendations 2020 - From ‘Patient’ to ‘Person’

Guest User
March 9, 2020
Background
ISPD Practice Recommendations 2020 - From ‘Patient’ to ‘Person’

This week, we will discuss the fresh-off-the-press ISPD recommendations on what they call as ‘prescribing high quality, goal directed’ PD. No mention of adequacy even in the title, in a subtle shade at the move away from numbers to things that really matter.

Tagged: peritoneal dialysis, guidelines, ISPD

joel topf
March 6, 2020
Commentary

Nice PEXIVAS vs MEPEX infographic

joel topf
March 6, 2020
Commentary

Confused about how PEXIVAS reversed MEPEX? Maybe this infographic will help.

Nice work by NSM intern Namrata Parikh.

Infographic PEXIVAS MEPEX 4.0.png

Tagged: pexivas, infographic, mepex

swapnil hiremath
February 24, 2020
Commentary

PEXIVAS: the Visual Abstract

swapnil hiremath
February 24, 2020
Commentary

Beautiful work here from Alex Meraz

PEXIVAS VA.jpg

If you are interested in the NEJM style, here is their own VA:

PEXIVAS VA NEJM.jpg

Tagged: visual abstract, Visual Abstract, pexivas, nejm, alex meraz

swapnil hiremath
February 24, 2020
Background

perPLEXed by ANCA? Let PEXIVAS show you the path to less steroids and the end of plasma exchange

swapnil hiremath
February 24, 2020
Background
perPLEXed by ANCA? Let PEXIVAS show you the path to less steroids and the end of plasma exchange

This week we discuss the long awaited PEXIVAS trial. Reduced dose steroids win, and PLEX loses. Or does it?

Tagged: pexivas, anca, trial, rct, nejm, verner

joel topf
February 11, 2020
Commentary

Visual Abstract on ANCA vasculitis and Myeloperoxidase Inhibition Attenuates Neutrophil Activation

joel topf
February 11, 2020
Commentary

Krithika Mohan came up big this with this week’s visual abstract

Tagged: mpo anca, visual abstract, Visual Abstract

swapnil hiremath
February 11, 2020
Background

Are ANCA actually attackers?

swapnil hiremath
February 11, 2020
Background
Are ANCA actually attackers?

We are now in GN territory this month - or rather ANCA Vasculitis month! First we start off with this paper from London, which uses some data from the RAVE trial along with additional experiments to show some intriguing results on the role of MPO.

Tagged: mpo anca, jasn, basic science, basic, mouse, tiff caza

Matt Sparks
February 6, 2020
news

Announcing the NSMC Internship Class of 2020

Matt Sparks
February 6, 2020
news
Announcing the NSMC Internship Class of 2020

The 6th class of NSMC interns is ready to go. Meet the new interns and then go follow them on Twitter so you don’t miss their excellent content.

Tagged: NSMC

swapnil hiremath
January 28, 2020
Commentary

GAD is still BAD: A Commentary

swapnil hiremath
January 28, 2020
Commentary
GAD is still BAD: A Commentary

A commentary from Prof Wagner, making the case that gadolinium remains toxic and we should remain wary of using it indiscriminately

Tagged: commentary, brent wagner, gadsnotbad, gadolinium

joel topf
January 27, 2020
Background

GAD ain't BAD

joel topf
January 27, 2020
Background
GAD ain't BAD

In early 2000s there was an epidemic….and then it died down. Have we successfully eliminated the scourge of NSF by appropriately changing our behaviour? Perhaps the pendulum has swung too much and needs to come back to the middle.

Tagged: gadsnotbad, gadolinium, mri, meta-analysis, jama int med

joel topf
January 27, 2020
Commentary

Gadolinium in CKD 4 , 5 and dialysis systematic review and meta analysis. The Visual Abstract

joel topf
January 27, 2020
Commentary

Vicki Sandys put together the visual abstract for this week’s NephJC

Tagged: gadsnotbad, jama, meta-analysis, gadolinium, Visual Abstract, visual abstract

joel topf
January 14, 2020
Commentary

The MMF Dosing Visual Abstract

joel topf
January 14, 2020
Commentary

Wow. Krystahl Andujar saved our bacon with a last minute visual abstract.

Tagged: mmf-dosing, visual abstract, Visual Abstract

swapnil hiremath
January 14, 2020
Background

Maybe MMF Measurement Matters?

swapnil hiremath
January 14, 2020
Background
Maybe MMF Measurement Matters?

We measure cyclosporine and tacrolimus levels. But don’t bother with mycophenolate levels - why is it? Is it too difficult? Does it not matter? NephJC tackles a different kind of study this time - a literature review, albeit conducted systematically.

Tagged: systematic review, pharmacology, Transplant, mmf-dosing, cathy quinlan, drug

Matt Sparks
January 7, 2020
news

The Top Nephrology Stories of 2019

Matt Sparks
January 7, 2020
news
The Top Nephrology Stories of 2019

The votes are in and counted. NephJC proudly presents the Top Nephrology Related stories of 2019. Note- The MENTOR trial was not included in this years voting since it made the Top stories list of 2017 when it was originally presented.

Tagged: Top Stories, News

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