Background
Brian Rifkin
A VALIANT effort to combat complement disorders ...

This week, we will discuss the VALIANT study, pegcetacoplan in C3G and IC MPGN.

A VALIANT effort to combat complement disorders with pegcetacoplan
news
Cristina Adriana Popa
Top Stories in Nephrology 2025

2025 was rich in successful stories. Here are the top 10 that impressed our audience.

Top Stories in Nephrology 2025
Background
Brian Rifkin
Dialyze Less, Recover More? AKI’s Chance to Get ...

This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.

Dialyze Less, Recover More? AKI’s Chance to Get LIBERATE-D
Background
Brian Rifkin
Fish Oil in Dialysis: A Big Catch or an Empty ...

Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?

Fish Oil in Dialysis: A Big Catch or an Empty Net
Background
Brian Rifkin
Attacking the Origin of IgAN: ORIGIN3 and ...

This week, we will discuss the phase 3 ORIGIN3 trial of atacicept, an APRIL/BAFF inhibitor for use in IgAN.

Attacking the Origin of IgAN: ORIGIN3 and Atacicept

Will PRESERVE preserve the contrast AKI status quo?

Will PRESERVE preserve the contrast AKI status quo?

This week, we will discuss the fresh-off-the-press NEJM paper on the utility of using NAC (vs placebo) or bicarb-based hydration (vs saline) in preventing contrast AKI. A medical reversal that has taken almost 2 decades...