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NephJC

Queue
Flozinator
Blog
PodCast
More
Club de Articulos
Code of Conduct
The Why, When and How
The NephJC Organization
Twitter Journal Club Primer
Who are we
Masthead
COVID19
Seminars in Nephrology
Regarding Twitter...
Newsletter
May 26, 2025
Background
Cristina Adriana Popa
Advance-HTN: Return of the systolic order – ...

This week, we will discuss a NEJM trial on uncontrolled hypertension: lorundrostat, an aldosterone synthase inhibitor, aims at the hormonal dark side driving resistance.

Advance-HTN: Return of the systolic order – Lorundrostat’s role in restoring balance
May 12, 2025
Background
swapnil hiremath
Double Trouble: ddAVP and the Bleeding Biopsy

This week, we will discuss a double header: two single centre ddAVP trials in kidney biopsy from India.

Double Trouble: ddAVP and the Bleeding Biopsy
April 28, 2025
Background
Cristina Adriana Popa
Kidney Allografts-Play With Fire, Get Burned

This week, we will discuss the prognostic role of microvascular inflammation in kidney transplantation. Can the capillaries whisper their damage in lesions before antibodies speak? Maybe this study compels us to treat the injury we see, not just the disease we can name…

Kidney Allografts-Play With Fire, Get Burned
April 14, 2025
Background
swapnil hiremath
Metformin- Should I Stay or Should I Go

This week, we will discuss another target trial emulation study. The FDA says to stop metformin at a GFR of 30. Are they right?

Metformin- Should I Stay or Should I Go
March 23, 2025
Background
Brian Rifkin
KDIGO 2025 ADPKD Guidelines Review

This week, we will discuss the first iteration of KDIGO’s 2025 guidelines on ADPKD.  These guidelines are a result of a decade of global collaboration between physicians, researchers, advocates, and patients. The guidelines incorporate ADPKD-specific care as well as many general CKD management practice points.


KDIGO 2025 ADPKD Guidelines Review
swapnil hiremath
June 11, 2024
Background

FLOWing with the SemagluTIDE

swapnil hiremath
June 11, 2024
Background
FLOWing with the SemagluTIDE

This week, we will discuss the blockbuster trial of 2024, FLOW. GLP1RAs have arrived in the nephrology realm.

Tagged: flow, semaglutide, glp1ra, nejm, NEJM, trial, RCT, rct, positive, diabetes, diabetic kidney disease, Diabetic kidney disease, diabetic nephropathy, sejal lakhani, rowan zyada

Pallavi Prasad
May 21, 2024
Background

The KDIGO 2024 CKD Guidelines: part 2

Pallavi Prasad
May 21, 2024
Background
The KDIGO 2024 CKD Guidelines: part 2

This week, we will discuss the second part of the 2024 CKD guidelines from KDIGO. Lots to chew on, so let’s dive in!

Tagged: kdigo-ckd, kdigo, KDIGO, guidelines, CKD, kavita vishwakarma, jasmine sethi

Divya Bajpai
May 21, 2024
Visual Abstract

KDIGO 2024 CKD guidelines part 2 - Visual Abstract

Divya Bajpai
May 21, 2024
Visual Abstract

Checkout the top 10 takeaways by KDIGO on the management of people with CKD. VA by Dr Vamsidhar Veeranki

Tagged: Vamsidhar Veeranki, kdigo-ckd, visual abstract, Visual Abstract

swapnil hiremath
May 7, 2024
Background

The KDIGO CKD 2024 Guidelines Part 1: Evaluation and Risk Stratification

swapnil hiremath
May 7, 2024
Background
The KDIGO CKD 2024 Guidelines Part 1: Evaluation and Risk Stratification

This week, we will discuss the 2024 KDIGO Guidelines on CKD, part 1. In this section we will discuss the first two chapters on CKD evaluation and risk stratification. Let’s dive in!

Tagged: medhavi gautam, stephanie Torres, kdigo, KDIGO, kdigo-ckd, guideline, guidelines, kidney international, ckd, CKD staging, cystatin c, risk score

Divya Bajpai
May 7, 2024
Visual Abstract

KDIGO CKD GUIDELINES - VISUAL ABSTRACT

Divya Bajpai
May 7, 2024
Visual Abstract

Check out the TOP 10 takeaways from KDIGO - CKD guidelines on evaluation of people with or at risk of CKD by NSMC Intern Stephanie Torres

Tagged: visual abstract, Visual Abstract, kdigo, ckd, stephanie Torres, kdigo-ckd, KDIGO

Divya Bajpai
April 22, 2024

Apolipoprotein E in Dense Deposit Disease and C3 GN - Visual Abstract

Divya Bajpai
April 22, 2024
Apolipoprotein E in Dense Deposit Disease and C3 GN - Visual Abstract

Is Apolipoprotein E a new biomarker for DDD and C3GN?

NSMC Intern Dr Jasmine Sethi decodes the recent study visually

Tagged: visual abstract, Visual Abstract, ddd, c3gn, jasmine sethi, apolipoprotein e

Jade Teakell
April 22, 2024
Background

Shedding Light on the Dense Matter of C3 Glomerulopathy

Jade Teakell
April 22, 2024
Background
Shedding Light on the Dense Matter of C3 Glomerulopathy

This week, we will discuss the role of ApoE in determining the subtypes of C3 Glomerulopathy.

Tagged: apolipoprotein e, c3gn, ddd, dense deposit disease, pathology, rangan, stephanie Torres, torres rodriguez, anvitha rangan, kidney international, Glomerulonephritis, glomerulonephritis, mpgn

swapnil hiremath
April 9, 2024
Background

Healing, Hype, or Harm: The NefIgArd trial

swapnil hiremath
April 9, 2024
Background
Healing, Hype, or Harm: The NefIgArd trial

This week, we will discuss the final results of the NEFIGARD trial with the GFR slope data. Is targeted release budesonide aka Nefecon really a way to provide steroid efficacy without steroid side effects?

Tagged: nefecon, NefigArd Trial, nefigard, lancet, positive, rct, RCT, jasmine sethi, anant pilavan, iga, igan, iga ne, iga nephropathy

Divya Bajpai
April 9, 2024
Visual Abstract

The NeflgArd Part B Visual Abstract

Divya Bajpai
April 9, 2024
Visual Abstract

Does targeted-release formulation of Budesonide improve kidney function in primary IgA Nephropathy? Check out the VA by NSMC Intern Anant Pilawan on NefIgArd part B trial

Tagged: visual abstract, Visual Abstract, Anant Pilawan, NefigArd Trial, iga nephropathy, Budesonide, nefecon, nefigard

Cristina Adriana Popa
March 26, 2024
Background

PRAECISely Predicting Preeclampsia

Cristina Adriana Popa
March 26, 2024
Background
PRAECISely Predicting Preeclampsia

This week, we tag along with NephMadness. It will be hard to stay impartial while discussing the role of angiogenic and antiangiogenic factors in severe preeclampsia prognosis.

Tagged: biomarker, validation, preeclampsia, Hypertension, diagnosis, Elba Medina, hypertension, kavita vishwakarma, nejm evidence, observational, praecis, PRAECIS

Divya Bajpai
March 26, 2024
Visual Abstract

PRAECIS - Visual Abstract

Divya Bajpai
March 26, 2024
Visual Abstract

NSMC Intern Elba Medina creates a crisp VA for the PRAECIS trial.

Also, we have some bonus VAs this time created for NephMadness by our VA editor Divya Bajpai!

Tagged: visual abstract, Visual Abstract, PRAECIS, Elba Medina, preeclampsia, neph, sflt1, DIvya Bajpai, praecis, pregnancy, Pregnancy

Divya Bajpai
March 12, 2024
Visual Abstract

Global disparities in kidney disease burden and care - Visual Abstract

Divya Bajpai
March 12, 2024
Visual Abstract
Global disparities in kidney disease burden and care - Visual Abstract

Check out the Visual abstract by NSMC intern Stephanie Torres on ”Global Disparities in Kidney disease burden and care”

Tagged: stephanie Torres, visual abstract, Visual Abstract, CKD, disparities, global kidney health atlas

swapnil hiremath
March 12, 2024
Background

The Worldwide Shadow of Kidney Disease

swapnil hiremath
March 12, 2024
Background
The Worldwide Shadow of Kidney Disease

This week, during kidney month and NephMadness season, we will discuss the USRDS report as well as the ISN Global Kidney Health Atlas report from 2024.

Tagged: usrds, global kidney health atlas, incidence, prevalence, lancet, Elba Medina, Vamsidhar Veeranki

swapnil hiremath
March 10, 2024
Background

The PROTECT-V platform - RENALISM no more?

swapnil hiremath
March 10, 2024
Background
The PROTECT-V platform - RENALISM no more?

This week on NephTrials we will discuss the PROTECT-V trial, a platform trial for preventing COVID-19 infections in the vulnerable kidney populations.

Tagged: nephtrials, manasi, platform trials, covid19, covid-19, rct, RCT, protect-v

swapnil hiremath
February 20, 2024
Background

Dialysis dreams and sleepless realities: the SLEEP-HD trial

swapnil hiremath
February 20, 2024
Background
Dialysis dreams and sleepless realities: the SLEEP-HD trial

This week, we will discuss the SLEEP-HD trial, which examined if trazodone or CBT are better than placebo in helping people sleep.

Tagged: Annals, annals, Cristina popa, cristina popa, swap, rct, sleep, sleep-hd, trazodone, trial, Trial, RCT, negative, hemodialysis, swapnil hiremath

Cristina Adriana Popa
February 19, 2024
Visual Abstract

The SLEEP-HD Visual Abstract

Cristina Adriana Popa
February 19, 2024
Visual Abstract

Check out the dreamy Visual Abstract by Cristina Popa

Any sleep potion for insomnia in patients on hemodialysis?

Tagged: hemodialysis, rct, RCT, trazodone, cbt, insomnia, Annals, Cristina popa, cristina popa, sleep-hd, sleep, dialysis, annals]

joel topf
February 13, 2024
Future Topic

🤔 Trainee Love and Breakup Letters to NephSIM

joel topf
February 13, 2024
Future Topic

Trainee Love and Breakup Letters to NephSIM: A Free, Mobile-Optimized, Nephrology Teaching Tool (Fattah, CJASN 2023)

Tagged: education

joel topf
February 13, 2024
Future Topic

🤔 Does BP lowering matter for the kidneys after all?

joel topf
February 13, 2024
Future Topic

Intensive BP Control in Patients with CKD and Risk for Adverse Outcomes (Ku, JASN 2023)

Tagged: hypertension, ckd

joel topf
February 13, 2024
Future Topic

🤔 AT receptor action and dementia

joel topf
February 13, 2024
Future Topic

Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries (Marcum, JAMA Open Network 2022)

Tagged: hypertension, dementia

joel topf
February 13, 2024
Future Topic

🤔 Starting ARB in hospitalized COVID, an RCT

joel topf
February 13, 2024
Future Topic

Angiotensin receptor blockers for the treatment of covid-19: pragmatic, adaptive, multicentre, phase 3, randomised controlled trial (Jardine, The BMJ 2022)

Tagged: arb, covid19, covid-19

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