This week, we will discuss a pilot trial of using mannitol to treat intradialytic hypotension. A daily occurence in our practice, hence providing some much needed data.
Can difelikefalin scratch uremic pruritus?
Patiromer, spironolactone and resistant hypertension.
Drying in Dialysis: The Peritoneal Dialysis Edition
Artificial Intelligence to Overcome Natural Stupidity
Can We Stop MUC-1 From Mucking Up the Kidney
Some cases of ADTKD are due to mutations of the MUC-1 gene, one mutation is a frame shift mutation that results in a premature stop codon. which results in accumulation of the abnormally short, and toxic protein MUC-1 fs . The researchers found a small protein, BRD4780, that reroute MUC-1fs to lysosomes, preventing proteinopathy and possibly altering the natural history of the disease.
