Background
Brian Rifkin
Is REACT (Renal Autologous Cell Therapy) the ...

This week, we will discuss the use of renal autologous cell therapy (REACT) in diabetic kidney disease.

Is REACT (Renal Autologous Cell Therapy) the “fifth pillar” in diabetic kidney disease?
Background
Brian Rifkin
2026 KDIGO Anemia Management Guidelines

This week, we will discuss 2026 KDIGO anemia management in patients with kidney disease

2026 KDIGO Anemia Management Guidelines
Background
Cristina Adriana Popa
To INFINITI and Beyond: SGLT2 Inhibitors in ...

This week, we aim for an INFINITe allograft lifespan. or flozination in kidney transplant.

To INFINITI and Beyond: SGLT2 Inhibitors in Kidney Transplant Patients
Background
Cristina Adriana Popa
POTCAST- K+ Pop and Arrhythmia Drop

This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.

POTCAST- K+ Pop and Arrhythmia Drop
Background
Brian Rifkin
A VALIANT effort to combat complement disorders ...

This week, we will discuss the VALIANT study, pegcetacoplan in C3G and IC MPGN.

A VALIANT effort to combat complement disorders with pegcetacoplan

Background

Creatinine to Cystatin C: Time to Change?

Creatinine to Cystatin C: Time to Change?

This week, we will discuss a paper from Nature Medicine. Cystatin C has been around for a while, but not taken off in routine practice. Is it time for it to do so? In this study, authors from Glasgow using the UKBiobank data show that cystatin C improves the prediction of bad outcomes.

Can difelikefalin scratch uremic pruritus?

Can difelikefalin scratch uremic pruritus?

This week we will be discussing the KALM-1 trial which was presented at the Late Breaking and High Impact Trial Session at the recently completed #KidneyWk. It was simultaneously published in the NEJM. Kalm-1 investigated whether difelikefalin, a opioid kappa agonist, decreased uremic pruritus.

Patiromer, spironolactone and resistant hypertension.

Patiromer, spironolactone and resistant hypertension.

The new generation of potassium binders bind potassium but can they improve patient outcomes? These second order questions are starting to be answered. Join us this week to discuss the use of patiromer and spironolactone in patients with resistant hypertension.The AMBER Study

Can We Stop MUC-1 From Mucking Up the Kidney

Can We Stop MUC-1 From Mucking Up the Kidney

Some cases of ADTKD are due to mutations of the MUC-1 gene, one mutation is a frame shift mutation that results in a premature stop codon. which results in accumulation of the abnormally short, and toxic protein MUC-1 fs . The researchers found a small protein, BRD4780, that reroute MUC-1fs to lysosomes, preventing proteinopathy and possibly altering the natural history of the disease.