swapnil hiremath

February 12, 2019

Background

The fault lies in our genes?

swapnil hiremath

February 12, 2019

Background

The fault, is not in our stars, or in our environment, but sometimes in ourselves. Nature, not just nurture, is more important than we knew. Join us, as we try to undertand the implications of this new research suggesting how many CKD cases have genetic underpinnings.

joel topf

January 28, 2019

Background

Nephrology Research. Are we improving?

joel topf

January 28, 2019

Background

We complain about the quality of kidney research but is there any meat there? Join us this week as we look at Chatzimanouil’s recent examination of the nephrology literature.

joel topf

January 14, 2019

Background

Vitamin D in Dialysis is a Dud

joel topf

January 14, 2019

Background

First chat of 2019 - showcasing again the honest brokers of nephrology trials with another negative trial. Also note we will be having a NephJC Asia chat starting this week!

joel topf

December 11, 2018

Background

Single-cell RNA sequencing in the spotlight

joel topf

December 11, 2018

Background

Single-cell RNA sequencing in the spotlight

This week, we go back to basic science with Jennie Lin leading us through two important papers on single cell RNA sequencing.

joel topf

December 2, 2018

Background

Lanreotide rubs the ADPKD lamp but there's no Genie

joel topf

December 2, 2018

Background

Lanreotide rubs the ADPKD lamp but there's no Genie

This week, we will discuss the use of lanreotide - a somoatostatin analogue, for the treatment of autosomal dominant polycystic kidney disease. An RCT, published in JAMA.

joel topf

November 26, 2018

Background

Sirolimus as a Savior for Skin Cancer?

joel topf

November 26, 2018

Background

Join us to discuss this extension of the TUMORAPA trial - in a joint session with the #DermJC. Should kidney transplant recipients with squamous cell cancer be switched to sirolimus?

swapnil hiremath

November 11, 2018

Background

There's just been AKI. So what do we do with the ACEi/ARB?

swapnil hiremath

November 11, 2018

Background

There's just been AKI. So what do we do with the ACEi/ARB?

There is AKI. You are ready to discharge the patient. Should you restart their ACEI/ARB? Or they were never on an ACEI/ARB - but surely with a history of heart failure, they should be on one? How do you decide? Join us to discuss some exciting new data

swapnil hiremath

October 30, 2018

Background

There’s Acid? Give Alkali! Does that really help?

swapnil hiremath

October 30, 2018

Background

There’s Acid? Give Alkali! Does that really help?

This week we discuss the BICAR-ICU trial from France. In patients who are critically ill with metabolic acidosis, does giving bicarb help improve survival? More importantly, does it help with kidney outcomes? Join us to discuss

joel topf

October 11, 2018

Background

Proposition 8

joel topf

October 11, 2018

Background

Proposition 8 is on the ballot. It pits the labor unions against the dialysis corporations. Simple right? Wrong. Check out the details and join us Oct 16.

swapnil hiremath

October 4, 2018

Background

The Structure behind the Function: Unravelling PKD by CryoEM

swapnil hiremath

October 4, 2018

Background

The Structure behind the Function: Unravelling PKD by CryoEM

This week, we discuss some amazing advances made in our understanding of the PKD protein - using a technology called CryoEM. Check out the video explainer and summary.

swapnil hiremath

September 21, 2018

Background

MesoAmerican Nephropathy: More Light on the Heat Hypothesis?

swapnil hiremath

September 21, 2018

Background

MesoAmerican Nephropathy: More Light on the Heat Hypothesis?

Join us as we discuss this study which meticulously collected data from Nicaragua to shed more light on the potential mechanism of mesoamerican nephropathy

swapnil hiremath

August 31, 2018

Background

Antibiotics are bad, the Stone Edition

swapnil hiremath

August 31, 2018

Background

September 4 and 5 we discuss kidney stones and antibiotics. How are the two related, you say? Join us. Find out more!

joel topf

August 18, 2018

Background

Atrial Fibrillation, Anticoagulation and Dialysis: Do We Finally Have A Better Option?

joel topf

August 18, 2018

Background

Atrial Fibrillation, Anticoagulation and Dialysis: Do We Finally Have A Better Option?

Retrospective analysis of apixaban vs warfarin for atrial fibrillation in dialysis patients.

joel topf

August 2, 2018

Background

#NephJCBookClub next Tuesday and Wednesday

joel topf

August 2, 2018

Background

#NephJCBookClub next Tuesday and Wednesday

The fourth annual NephJC Summer Book Club is here and we are reading and discussing, Siddhartha Mukherjee's The Laws of Medicine, Field Notes from an Uncertain Science.

swapnil hiremath

July 23, 2018

Background

Water, water everywhere, but how much to drink?

swapnil hiremath

July 23, 2018

Background

Water, water everywhere, but how much to drink?

How much water should we drink? Does drinking more water help flush the kidney? Join us as we discuss the definitive trial done to answer this question.

swapnil hiremath

July 7, 2018

Background

RELIEF: More Fluids mean Less AKI?

swapnil hiremath

July 7, 2018

Background

Randomized controlled trial of restrictive versus liberal IV fluid strategy around abdominal surgery.

swapnil hiremath

June 24, 2018

Background

Is Renal Denervation Innervated Again?

swapnil hiremath

June 24, 2018

Background

Check out the overall summary of all our renal denervation trial bonanza from 2018.

swapnil hiremath

June 24, 2018

Commentary, Background

RADIANCE SOLO: Denervation with a Difference?

swapnil hiremath

June 24, 2018

Commentary, Background

RADIANCE SOLO: Denervation with a Difference?

This is the summary of the RADIANCE SOLO trial, of renal denervation using an intravascular ultrasound, in patients not on medications.

swapnil hiremath

June 23, 2018

Commentary, Background

SPYRAL ON: Renal Denervation in Patients ON Medications

swapnil hiremath

June 23, 2018

Commentary, Background

SPYRAL ON: Renal Denervation in Patients ON Medications

This is the summary of the SPYRAL HTN-ON trial - of renal denervation in patients on 1-3 medications.

swapnil hiremath

June 22, 2018

Commentary, Background

SPYRAL OFF: Can Renal Denervation Reduce Blood Pressure in Hypertension?

swapnil hiremath

June 22, 2018

Commentary, Background

SPYRAL OFF: Can Renal Denervation Reduce Blood Pressure in Hypertension?

This is the summary of one of the three RDN trials we are discussing - SPYRAL HTN-OFF, which examined the effect of renal denervation in patients with mild hypertension, who were off medications.